(精编)【医学课件】 Update on Methods for Cleaning and Disinfection of Environmental Surfaces教学课件.pptVIP

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(精编)【医学课件】 Update on Methods for Cleaning and Disinfection of Environmental Surfaces教学课件.ppt

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No-Touch Room Decontamination Methods In many facilities, 50% of high-touch surfaces are wiped by housekeepers at the time of terminal room cleaning In response, “no-touch” automated systems have been developed to decontaminate patient rooms after discharge Examples include: Aerosolized hydrogen peroxide Hydrogen peroxide vapor systems Gaseous ozone Saturated steam systems Mobile ultraviolet and pulsed-Xenon light devices High-Intensity Narrow-Spectrum light Carling PC et al. Am J Infect Control 2010;38 (5 Suppl 1):S41 Otter JA et al. J Hosp Infect 2013;83:1 * Aerosolized Hydrogen Peroxide Dry Mist Systems Portable units aerosolize hydrogen peroxide 5-6% hydrogen peroxide +/- 50-60 ppm silver plus stabilisers Aerosolized (droplets – not gas) have particle size of 0.5-12 μm Systems use passive aeration. Hydrogen peroxide is left to degrade naturally Cycle time 2 hr for a single room Examples of hydrogen peroxide aerosol systems * Aerosolized Hydrogen Peroxide Generally reduces indicator spores by 4 logs Cultures obtained Before/After cycles have demonstrated significant reductions in bacterial (including spore) counts in laboratory settings and patient care areas Did not completely eradicate C. difficile spores in 2 studies One system has sporicidal claim from EPA in USA Andersen BM et al. J Hosp Infect 2006;62:149 Shapey S et al. J Hosp Infect 2008;70:136 Bartels MD et al. J Hosp Infect 2008;70:35 Barbut F et al. Infect Control Hosp Epidemiol 2009;30:515 Piskin N et al. Am J Infect Control 2011;39:757 Landelle et al. ICHE 2013;34:119-124 Mitchell BG et al. BMJ Open 2014;4: doi: 10.1136/bmjopen-2013-004522 * Aerosolized Hydrogen Peroxide More recently, an aerosolized hydrogen peroxide system which emits 7.5% H202 was tested for activity against spores on G. stearothermophilus and 2 strains of C. difficile on carriers located 80 cm from device After a 1-hr exposure in a ?-open drawer, few C. difficile spores were killed a 105 log reducti