食品安全目标的建立及应用幻灯片.pptVIP

三、 FSO的工作原理 botulinum 减少12 log pH控制在4.6以下 巴斯德杀菌70°C 度2分钟。 A concentration of salmonellae in powdered milk below 1 cfu/100 g. pathogenic E. coli 在包装果汁中不超过1 cfu/10 升 From Leon Gorris From Martin Cole 三、 FSO的建立 （一） 建立与执行FSO的科学考Scientific considerations for establishing And implementing FSO； （二）利用FSO方法，建立降低食源性李氏特病的案例分析 Case Study--use of food safety objectives as a tool for reducing foodborne listeriosis Scientific considerations for establishing And implementing FSO (1) 所关注的公共卫生问题及对管理需求的鉴别。Identification of a public health concern and the need for management actions. (2) 风险水平的评估Evaluation of the level of risk (e.g., by conducting a risk assessment). (3) 公共卫生目标的清晰度Articulation of the public heath goal. Scientific considerations for establishing And implementing FSO (4) 实现公共卫生目标的最大暴露水平的确定Determination of the maximum level of exposure that would achieve the public health goal --- this is the FSO. (5)执行或遵照FSO的可行性的评估Evaluation of the feasibility of complying with the FSO. (6) FSO在食品企业的执行 Implementation of the FSO by the industry. Case Study--use of food safety objectives as a tool for reducing foodborne listeriosis 1、 关注的公共卫生问题public health concern Listeria monocytogenes is a foodborne pathogen that can cause listeriosis. there are an estimated 2500 cases of listeriosis in the USA per year 。Invasive listeriosis has an estimated fatality rate of 20–30% of those who become ill 2、 风险水平the level of risk Many food products have been linked to listeriosis, including cold-smoked fish. Depending on the processing plant, between 3% and 100% of cold-smoked salmon samples can be positive for the pathogen in 25 g samples. Case Study--use of food safety objectives as a tool for reducing foodborne listeriosis 3、公共卫生目标 the public heath goal In the USA, a public health objective of 0.25 cases of listeriosis per 100,000 population per year has been proposed（(Healthy People 2010） An ALOP for an infectious agent should not be