Amino Acids, Proteins, Nucleic Acids：氨基酸，蛋白质，核酸.ppt

Amino Acids and Proteins Amino Acids Synthesis of Amino Acids Strecker Synthesis Gabriel Synthesis Biosynthesis Transamination Polypeptides and Proteins Complete hydrolysis of a polypeptide gives: Gly, 3 Leu, 2 Tyr, 2 Phe, 2 Lys, Ser, 2 Met, Ala, Val, Ile, Arg, Pro Cyanogen bromide generates a tripeptide, a heptapeptide, and an octapeptide; each is sequenced: Leu-Pro-Phe Gly-Leu-Trr-Phe-Lys-Ser-Met Ala-Leu-Tyr-Lys-Val-Ile-Arg-Met Partial hydrolysis with trypsin gives a tripeptide, a tetrapeptide, a pentapeptide, and a hexapeptide; each is sequenced: Val-Ile-Arg Met-Leu-Pro-Phe Gly-Leu-Tyr-Phe-Lys Ser-Met-Ala-Leu-Tyr-Lys What is the sequence for the original polypeptide? Polypeptide and Protein Synthesis Protecting Groups Secondary Structures of Polypeptides and Proteins Pleated Sheet Tertiary Structures of Polypeptides and Proteins Enzymes Carboxypeptidase A Activating Groups Automated Synthesis ?-Helix L-isoleucine zwitterion Carboxypeptidase Trypsin, chymotrypsin BrCN