MR Airway Pressure Device - CAE UsersMR气道压力装置CAE用户.pptVIP

Overview Motivation Problem Statement Client Specifications Background Information Commercially Available Devices Preliminary Design Design Components Mouthpiece Valve Transducer Future Work Motivation Dr. Haughton is radiologist at UW-Hospital with a specialty in neuroradiology Research interest in CSF disorders Device needed to measure airway pressure during MR imaging Problem Statement Our client Dr. Haughton is currently studying CSF flow during Valsalva maneuvers performed by children with Chiari I malformations. Current research suggests that CSF flow decreases during Valsalva maneuvers in these patients. The airway pressure device would help monitor the exhalation force exerted by each child during a Valsalva maneuver in the MR suite. Knowing the pressure exerted by each patient in the study would be extremely beneficial for data analysis and accuracy. Client Specifications Device to measure airway pressure during Valsalva maneuver in pediatric patients with Chiari I malformations ?Needs to be MR compatible ?Pressure must be measured from beginning of Valsalva through mid expiration ?Small to minimize dead air space ?Usable by both alert and anesthetized patients Chiari I Malformations Valsalva Maneuver Expiratory effort against a closed glottis Increases pressure within the thoracic cavity Available Devices Generally assess lung health Use differential pressure transducer Not usable in the MR environment Examples: MR Background Main Field? No Ferromagnetic Materials MR Background Main Field? No Ferromagnetic Materials MR Background Main Field? No Ferromagnetic Materials MR Background Main Field? No Ferromagnetic Materials Preliminary Design Preliminary Design Mouthpieces Rigid Plastic Low dead space Disposable or easy to sanitize Valves Balloon Shutter Auto Transducers Manometers Diaphragm w/ strain gauge Design Matrix - Valves Design Matrix - Mouthpieces Potential Problems Potential artifacts Shielding equipment Valve perform