Magnetic Resonance Imaging Measures of Brain Structure to Predict Antidepressant Treatment Outcome in Major Depressive Disorder(脑结构的磁共振成像预测抑郁症的抗抑郁治疗效果).pdfVIP
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EBioMedicine 2 (2015) 37–45
Contents lists available at ScienceDirect
EBioMedicine
j ournal homepage:
Original Article
Magnetic Resonance Imaging Measures of Brain Structure to Predict
Antidepressant Treatment Outcome in Major Depressive Disorder
Mayuresh S. Korgaonkar a,b, William Rekshan c,d, Evian Gordon a,c,d, A. John Rush e, Leanne M. Williams a,f,g,
Christine Blasey h, Stuart M. Grieve a,i,j ,⁎
a The Brain Dynamics Centre, Westmead Millennium Institute, Sydney Medical School, Sydney, NSW, Australia
b Discipline of Psychiatry, Sydney Medical School, The University of Sydney, Westmead Hospital, Sydney, NSW, Australia
c Brain Resource Ltd, Sydney, NSW, Australia
d Brain Resource Ltd, San Francisco, CA, USA
e Duke-National University of Singapore, Singapore
f Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA
g Sierra-Pacifi c Mental Illness Research, Education, Clinical Center (MIRECC), Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
h PGSP-Stanford University Consortium, Palo Alto, CA, USA
i Sydney Translational Imaging Laboratory, Charles Perkins Centre and Sydney Medical School, University of Sydney, NSW 2006, Australia
j Department of Radiology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW 2006, Australia
a r t i c l e i n f o a b s t r a c t
Article history: Background: Less than 50% of patients with Major Depressive Disorder (MDD) reach symptomatic remission with
Received 21 October 2014 their initial antidepressant medication (AD
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