胃肠肝胆消化系统 课件.ppt

VII GI SECRETIONS;Exocrine of the GI tract;VII.1 Salivary secretion;Salivary gland;Secretion;Functions of Salivary Secretion;Control of salivary secretion;VII.2 Gastric secretion;Temporary store of ingested material Dissolve food particles and initiate digestive process Control delivery of contents to small intestine Sterilize ingested material Produce intrinsic factor (Vitamin B12 absorption);;Gastric gland cells;Composition and function of gastric secretions;Composition and function of gastric secretions;;;HCl secretion;;;;Gastric Mucus-bicarbonate barrier;Intrinsic Factor;VII.3 Regulation of Secretion;Control of Gastric Acid Secretion;Endocrine gland cells of gastric pits;stimulatory signals of Gastric Secretions;;;Gastric secretion during digesting food;Mechanisms Stimulating Gastric Acid Secretion in Cephasic Phase;;Gastric Phase;Intestinal Phase Account for about 5% of secretion Primarily hormonal – denervated stomach will be stimulated to secrete acid by protein in duodenum Hormone still unknown Very small number of G-cells in duodenum also release gastrin;Regulation of Gastric Secretions occurs via 3 phases; Regulation of gastric secretion;Mechanisms Inhibiting Gastric Acid Secretion;VIII. Secretion of the pancreas;Secretion of the pancreas;;Anatomical Structure Acini Ducts Pancreatic Duct ;Zymogens (酶原）;Cleave peptide bonds Hydrolyze DNA/RNA Collagen digestion Phospholipids to fatty acids Triglycerides to fatty acids+ glycerol Starch to maltose + glucose ;Activation of pancreatic proteases;;;Control of Pancreatic Function;Control of pancreatic secretion;Control of pancreatic secretion;;;Control of Pancreatic Function;;IX Biliary secretion;Structure/Function of Liver;54;Secretion and storage of bile;Emulsification of fats Increased absorption of lipids into enterocytes (include vitamin A, D, E, K) Increased synthesis and secretion of bile Cholesterol excretion (only route) Excretion of breakdown products of haemoglobin (bilirubin，胆红素) ;(a) A molecula