容量治疗推荐.pptVIP

* * 平均量在3升，最高量33升。 * 晶胶比超过1;2 ,是考虑到晶体有利于肾功能。 * * “ P values were determined with the use of the chi-square test. For the primary outcome variable (death during intensive care), the P value has been corrected for the repeated interim analyses, according to the method of Lan and DeMets; the unadjusted P value is 0.005. Sequential interim analyses were not performed for the other variables, and nominal (unadjusted) P values are given for these comparisons.” p. 1362 28天没有明显差别。90天的死亡率，HES组高，但P值是0.01，没有显著差异 * * 前14天想差不大，第21天曲线有明显分开。 * 显著差异 * 晶体组好于胶体组;数字是翻倍，明显增加，费用 住院天数等。。。不仅统计学有意义，而且有临床意义。输血明显增加，可能是血液滤过量增加 * * “ P values were determined with the use of the chi-square test. For the primary outcome variable (death during intensive care), the P value has been corrected for the repeated interim analyses, according to the method of Lan and DeMets; the unadjusted P value is 0.005. Sequential interim analyses were not performed for the other variables, and nominal (unadjusted) P values are given for these comparisons.” p. 1362 第一组; 小于22ml组，没有显著差异，但是胶体组还是高。 第二组：大于22ml组，非常显著差异，有统计学意义，说明剂量超过，感染患者的死亡率升高的非常多，因此，任何情况下不要超过厂家推荐剂量。 * 大剂量组，病情更加严重，在ICU时间明显增加，需要肾脏替代治疗天数增加。。。。。大剂量更易引起损害 * “ P values were determined with the use of the chi-square test. For the primary outcome variable (death during intensive care), the P value has been corrected for the repeated interim analyses, according to the method of Lan and DeMets; the unadjusted P value is 0.005. Sequential interim analyses were not performed for the other variables, and nominal (unadjusted) P values are given for these comparisons.” p. 1362 28天小剂量组：没有统计学差异，但是胶体还是高 * “ P values were determined with the use of the chi-square test. For the primary outcome variable (death during intensive care), the P value has been corrected for the repeated interim analyses, according to the method of Lan and DeMets; the unadjusted P value is 0.005. Sequential interim analyses were not performed for the other variables, and nominal (unadjus