中国抗感染病药物现状.pdfVIP

Current Situation of Medicine used for Infectious Disease in China 中国抗感染病药物现状 Wang Jun Zhi (王军志) National Institute for Control of Pharmaceutical Biological Products , NICPBP （中国药品生物制品检定所) Outline • Development of Biological Products in China 中国生物制品的发展历史简介 • Present Situation of Biologics for Prophylaxis (vaccine)预防用生物制品 • Present Situation of Biologics for Therapeutic use 治疗用生物制品 • Chemical Drugs of anti-infectious diseases 抗感染化学药 • Chinese Traditinal MedicineCTM 抗感染中药 Development of Biological Products in China The research, production, and application of biological products in China started since 1919. Biological products developed slowly and in small scale, only several species before 1949. At present time, China could produce over 200 kinds of biological products(Vaccines, Antitoxins/Antisera, Blood products,Cytokines , and also developed many new prophylaxis and therapeutic biological products continuously. 我国从1919年开始研究、生产和使用生物制品。在1949年以前的30年中，生 物制品发展缓慢，规模很小,只有几十个品种。目前生产使用了细菌类、病 毒类、毒素、抗毒素、抗血清、血液制品、细胞因子、微生态制剂、重组药 物、休内及体外诊断试剂等各类生物制品200多个品种，并且还在不断地研 制和生产出防治疾病所需要的各种新生物制品。 Before 1980’s almost biological products had been produced by 6 national institutes of biological products in Beijing, Shanghai , Changchun, Lanzhou, Wuhan, Kungming. These national institutes could produce the several vaccines up to 1 billion doses a year, which could meet the demand of vaccinating the whole nation. 在生物制品制造业方面，1980年代以前主要由北京、长春、成都、兰州、 上海、武汉、昆明6大卫生部生物制品研究所承担。其中疫苗每年生产近10 亿人份，满足了我国防疫预防接种的数量要求。 In the 1980’s,biological products industry was booming in China, there are more than 200 enterprises engaged in this field. Varieties and number of biological products increased significantly. • 20世纪80年代后，我国生物制品事业跨入了高速发展的新时期，生物制品 企业超过了200多家。生产的种类、型别、剂型也大