氮杂环席夫碱及其配合物的合成、晶体结构与抑菌活性研究-应用化学专业论文.pdf.docxVIP

ABSTRACTIn the past decades, the /dict_result.aspx?searchword=%e6%b0%ae%e6%9d%82%e7%8e%afamp;tjType=sentenceamp;styleamp;t=nitrogen%2Bheterocyclicnitrogen heterocyclic Schiff base and their metal complexes have attracted a great deal of attention because of their biological activities and pharmacological properties such as antibacterial, anticancer, anti-inflammatory, antidepressant effects and so on. So it is important for the synthesis and study of /dict_result.aspx?searchword=%e6%9c%89%e6%9c%ba%e8%8d%af%e7%89%a9amp;tjType=sentenceamp;styleamp;t=organic%2Bmedicamentorganic medicament and functional complexes using the combination of multifunctional nitrogen heterocyclic Schiff base ligands.In order to further enrich and extend the studies on the /dict_result.aspx?searchword=%e6%9c%89%e6%9c%ba%e8%8d%af%e7%89%a9amp;tjType=sentenceamp;styleamp;t=organic%2Bmedicamentorganic medicament and functional complexes, such as predetermination of molecular architectures and the properties of the complexes, seven novel aromatic nitrogen heterocyclic Schiff base compounds and seven transition metal complexes have been synthesized and characterized by single crystal X-ray diffraction on the basis of the previous work. The crystal structures of the compounds were determined. The antibacterial activities of the compounds and the complexes have also been investigated preliminarily. There are four parts in the thesis.The synthesis and /dict_result.aspx?searchword=%e7%94%9f%e7%89%a9%e6%b4%bb%e6%80%a7%e7%a0%94%e7%a9%b6amp;tjType=sentenceamp;styleamp;t=biological%2Bactivity%2Bstudybiological activity study for Schiff base ligands and their transition metal complexes were introduced. On the basis of which, the research target and method of the paper were put forward.Seven /dict_result.aspx?searchword=%e6%b0%ae%e6%9d%82%e7%8e%afamp;tjType=sentenceamp;styleamp;t=nitrogen%2Bheterocyclicnitrogen heterocyclic Schiff base have been synthesized: four Schiff base derived from PMBP, two single Sc