Heterogeneity of Stimulant Dependence A National Drug Abuse Treatment Clinical Trials Network Study精编.pdfVIP

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Heterogeneity of Stimulant Dependence A National Drug Abuse Treatment Clinical Trials Network Study精编.pdf

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Heterogeneity of Stimulant Dependence A National Drug Abuse Treatment Clinical Trials Network Study精编

NIH Public Access Author Manuscript Am J Addict . Author manuscript; available in PMC 2010 May 1. N Published in final edited form as: I H Am J Addict . 2009 ; 18(3): 206–218. doi:10.1080/10550490902787031. - P A A u Heterogeneity of Stimulant Dependence: A National Drug Abuse t h o r Treatment Clinical Trials Network Study M a n 1 1 1 2 u Li-Tzy Wu, ScD , Dan G. Blazer, MD, PhD , Ashwin A. Patkar, MD , Maxine L. Stitzer, PhD , s 3 2 c Paul G. Wakim, PhD , and Robert K. Brooner, PhD r i p t 1 Duke University School of Medicine, Department of Psychiatry and Behavioral Sciences, Duke Clinical Research Institute, Durham, North Carolina 2 Johns Hopkins University School of Medicine, 3 Department of Psychiatry and Behavioral Sciences, Baltimore, Maryland National Institute on Drug Abuse, Bethesda, Maryland Abstract N I H We investigated the presence of DSM-IV subtyping for dependence on cocaine and amphetamines - P (with versus without physical dependence) among outpatient stimulant users enrolled in a multisite A study of the Clinical Trials Network (CTN). Three mutually exclusive groups were identified: A primary cocaine users (n = 287), primary amphetamine users (n = 99), and dual users (cocaine and u t h amphetamines; n = 29). Distinct subtypes were examined with latent class and logis