(内分泌系统)Nuclear Medicine in Endocrine System知识介绍.pptVIP

(内分泌系统)Nuclear Medicine in Endocrine System知识介绍.ppt

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(内分泌系统)Nuclear Medicine in Endocrine System知识介绍.ppt

Nuclear Medicine in Endocrine System;核医学(Nuclear Medicine);;*;Content;放射性药物 Radiopharmaceuticals ;The indications for scintigraphic thyroid imaging;Normal imaging;Ectopic Thyroid Tissue. ;Substernal thyroid ;Thyroid Nodules ; 冷/凉结节 Cold or cool nodule;;;Discordant Thyroid Nodule ;Diffuse Toxic Goiter (Graves Disease) ;Multinodular Gland ;;Subacute granulomatous thyroiditis;Subacute thyroiditis; Assessment thyroid remnant;Congenital Organification Defect ;RAIU is based on the principle that the administered radiopharmaceutical is concentrated by the thyroid gland in a manner that reflects the gland’s handling of stable dietary iodine and therefore the functional status of the gland. ;To differentiate Graves disease from subacute thyroiditis or factitious hyperthyroidism. To determine how much activity to administer as a treatment dose for hyperthyroidism radioiodine therapy.; RAIU Technique ;Formula ;;RAIU ;Factors Affecting Iodine Uptake;Parathyroid imaging and localization ; PTH;parathyroid adenomas location;Imaging parathyroid adenomas ;Normal parathyroid scan;Parathyroid adenoma;Localization by SPECT/CT;;Radioiodine Therapy ; 131I treatment of hyperthyroidism ;甲状腺功能亢进症 (Hyperthyroidism) ;病因 ?(Etiologies);;;;;甲状腺相关性眼病 (Thyroid related opthalmopathy);胫前粘液性水肿 (Pretibial Myxedema);Choice of Treatment;内科:疗效肯定、很少引起永久性甲低 疗程长、易复发、过敏反应、骨髓抑制、肝功能损害 手术:疗效确切,起效快,复发率低 永久性甲低,并发症,手术瘢痕 131I: 疗效确切、简便安全、复发率低,并发症少、费用低 永久性甲低 诱发或加重突眼 ;Treatment Choice Decision;131I治疗甲亢的原理;交叉火力效应 Cross-fire effect;131I治疗后甲状腺组织变化;Radiation Absorbed Dose from 131I ;131I Treatment;;;适应证 Indications;禁忌证 Contraindications ; ;计算公式 Calculation Formula;剂量调整因素 Dose Consideration ;病人准备 Patient preparation ;Radiation safety after treatment with 131I;Results of Therapy;Short-term effects of RAI;Long-term effects of RAI;现实目标: 治愈甲亢,而不是避免甲减的发生。 The goal should be cure of hyperthyroid rather than avoidance of hypothyroid. ?;;;;;分化型甲状腺癌 (Differenti

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