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(内分泌系统)英文版甲状腺疾病相关治疗药36.ppt
Chapter 36
Thyroid Hormones and Antithyroid Drugs
Department of pharmacology
Liming zhou
2015.10;;;Thyroid hormone—synthesis and secretion;;Thyroid hormone—intracorporal process;;;;;;;Thiourea —【 Mechanism 】 ;;;;Thiourea—adverse effects;;;;;;;;;Thioureas inhibit the synthesis of thyroid hormones. Propythiouracil can also block the conversion of T4 to T3 in peripheral tissues.;131I exerts a destruction of thyroid gland by beta particles.
The major indications for the therapeutic use of thyroid hormones are for hormone replacement therapy in patients with hypothyroidism or cretinism, and antithyroid drugs are for the treatment of hyperthyroid individual.;131I exerts a destruction of thyroid gland by beta particles.
The major indications for the therapeutic use of thyroid hormones are for hormone replacement therapy in patients with hypothyroidism or cretinism, and antithyroid drugs are for the treatment of hyperthyroid individual.;1. Illustrate the influence of ?drug dose on the drug effects, take the effects of ?iodine on the thyroid function?
2. Try to explain the purpose of thiourea and iodine used on the hyperthyroidism preoperative?
?
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