感染性心内膜炎讲解材料.ppt

Infective Endocarditis;Introduction;Microbiology;Classification;Epidemiology;HACEK organisms;Pathogenesis;Modes of endothelial injury;Venturi Effect;Pathology ;Microscopy;Predisposing Factors;Pathophysiology;Pathophysiology (cont.);Pathophysiology(cont.2);Clinical Features;ABE and SBE;Peripheral Manifestations;Osler’s Node;Bleeding;Conjunctival Petechiae;Splinter Hemorrhage;Roth Spot;Clubbing;Lab Investigations;Diagnosis;Diagnosis-Duke Criteria;Diagnosis-Duke Criteria (cont.);Diagnosis-Duke Criteria (cont.2);Diagnosis-Duke Criteria (cont.3);“Echo should be done in all cases of suspected endocarditis.”;Differential Diagnosis;Treatment;Antibiotic Therapy;Antibiotic Therapy(2);Antibiotic Therapy(3);Surgical Treatment of Intra-Cardiac Complications;Surgical Treatment of Intra-Cardiac Complications(2);Surgical Treatment of Intra-Cardiac Complications(3);Prevention;Prevention – the procedure;Prevention – the underlying lesion;Prevention – the underlying lesion(2);Chemoprophylaxis;Adult Genitourinary or Gastrointestinal Procedures High Risk Patients Standard Regimen Before procedure (30 minutes): Ampicillin 2g IV/IM AND Gentamicin 1.5 mg/kg (MAX 120 mg) IM/IV After procedure (6 hours later) Ampicillin 1g IM/IV OR Amoxicillin 1g PO Penicillin Allergic Complete infusion 30 minutes before procedure Vancomycin 1g IV over 1-2h AND Gentamicin 1.5 mg/kg IV/IM (MAX 120 mg) Moderate Risk Patients Standard Regimen Amoxicillin 2g PO 1h before OR Ampicillin 2g IM/IV 30m before Penicillin Allergic Vancomycin 1g IV over 1-2h, complete 30m before ;Bring Home Message;Thank you！;Predisposing Conditions;Nonbacterial Thrombotic Endocarditis;Infection;Streptococci in IE;Viridans Streptococci;Other Streptococci;Enterococcus;Staphylococci;Fungi;Other Organisms;Diagnosis;Diagnosis;Use of Echo in Diagnosis of IE;Use of Echo in Diagnosis of IE;Use of Echo in Diagnosis of IE;Medical Management;Culture Nega