近红外无创血糖测量——基于耳垂部位检测的可行性分析-near infrared noninvasive blood sugar measurement - feasibility analysis based on earlobe detection.docxVIP

目录第一章绪论..........................................................................................11.1人体近红外无创血糖检测的背景意义..............................................................11.2人体近红外无创血糖检测的研究进展..............................................................21.3人体近红外无创血糖检测中存在的难题.........................................................31.4人体近红外无创血糖应用的测量部位概述.....................................................51.5本论文的研究内容和主要工作安排.................................................................6第二章近红外无创血糖检测的理论基础..............................................82.1描述光在生物组织中传播用到的光学参数......................................................82.2生物组织中光传播的蒙特卡洛模拟方法........................................................112.3近红外无创血糖测量的基本原理...................................................................152.4浮动基准方法理论及原理...............................................................................172.5近红外无创血糖检测中常用的化学计量学方法............................................192.6小结....................................................................................................................21第三章在生理上选取耳垂部位进行血糖测量的可行性研究...........223.1耳垂和指尖、手掌、前臂测量部位的生理特征比较...................................223.1.1人体皮肤分层及皮下组织的解剖结构介绍......................................223.1.2指尖、手掌、前臂和耳垂的皮肤分层结构......................................233.2耳垂内毛细血管全血和前臂内静脉全血的葡萄糖浓度关系.......................273.3OGTT中耳垂和指尖测量部位的血糖浓度的变化过程比较283.4OGTT中耳垂和前臂内侧测量部位的血糖浓度的变化过程比较293.5对耳垂测量部位进行血糖测量的可行性评价...............................................303.6小结...................................................................................................................30第四章基于蒙特卡洛模拟方法的对耳垂的近红外光谱特性的仿真研究..............................................................................................................314.1耳垂位置浮动基准点的存在特性研究...........................................................314.1.1耳垂皮肤五层模型下对漫反射光强的蒙特卡洛模拟......................314.1.2耳垂部位的个体差异对浮动基准点的影响模拟..............................324.2耳垂部位对透射光强的蒙特卡洛模拟.........................