广东地区HIVAIDS患者中医证型分布规律初步研究.docVIP

广东地区HIVAIDS患者中医证型分布规律初步研究 　　摘 要：目的：探讨广东地区HIV/AIDS患者的中医证型分布规律及其与疾病进展的关系。方法：对2003年1月-2007年12月广州市第八人民医院门诊及住院病人进行流行病学和四诊信息进行调查与分析。结果：广东地区艾滋病患者总体证型以气阴两虚肺肾不足最多见，无症状期以肝郁气滞火旺型为多，发病期则多见气阴两虚肺肾不足；基本证型以热证居多，无症状期以热证多见，发病期则为虚证和虚实夹杂证增多；女性以气血双亏型和肝郁气滞火旺型居多， 男性以热毒内蕴痰热壅肺和肝经风火湿毒蕴结居多；虚证和虚实夹杂证患者的体重中位数比较小，热证和瘀血证患者的体重中位数比较大。分析CD4+ T淋巴细胞计数与证型的关系发现：CD4+在0～200cell/μL之间的病人以气阴两虚肺肾不足、脾肾亏虚湿邪阻滞为主，CD4+在200～350cell/μL之间的病人以肝郁气滞火旺和气血双亏为多， CD4+在350cell/μL以上的两组病人均以肝郁气滞火旺为最常见的证型；气血双亏、肝郁气滞火旺、痰热内扰和气郁痰阻瘀血内停型患者的CD4+ T淋巴细胞水平比较高，而热毒内蕴痰热蕴肺、气阴两虚肺肾不足和脾肾亏虚湿邪阻滞这3类证型的患者CD4+ T淋巴细胞水平比较低，基本证型中热证和瘀血证的中位CD4+计数比较高，而虚实夹杂型的CD4+计数水平最低。结论：艾滋病患者以热证居多，无症状期以热证为主，发病期则虚证和虚实夹杂证增加，中医辨证证型与CD4+T淋巴细胞计数、性别和体重密切相关。 　　关键词：艾滋病；证型；CD4+；体重 　　中图分类号：R212.91 　　文献标识码：A文章编号： 　　1673-7717（2008）05-0958 　　-04 　　Investigation of TCM Syndrome in HIV/AIDS Patients of Guangdong 　　?? 　　CEN Yu?wen?1, FU Lin?chun?1, TAN Xing?hua?2,ZHANG Miao?miao?1,MA Bo?yan?1?（ 　　1.Guangzhou University of Chinese Medicine，Guangzhou 510450,Guangdong,China；? 　　2.The 8th Peoples Hospital of Guangzhou，Guangzhou 510060,Guangdong,China 　　 　　Abstract：Objective:To explore the distributing rule of traditional Chinese medical(TCM) syndrome in HIV/AIDSpatients. Methods: The epidemiologyand TCM examination information of 223 HIV/AIDS patients were investigated, CD4+ T lymphocyte count were tested,the data were analyzed with Independent Samples T test and One-way ANOVA using SPSS 13.0. Results: 12 TCM syndromes and 5 basic TCM syndromes were diagnosed.The leading syndrome of HIV/AIDS patient was Qi and Yin DeficinecyLung and Kidney Deficiency.In the phases of HIV infector,the main syndrome were Stagnation of Liver-qiFlaming-up of Liver-fire,while in the phases of AIDS, the main syndrome was Qi and Yin DeficinecyLung and Kidney Deficiency. The leading basic syndrome of HIV/AIDS was Heat Syndrome.In the phases of HIV infector,the main syndrome were Heat Syndrome,while in the phases of AIDS, there were more patient appear syndrome of Deficiency Syndromeand Excess and Defici