心脏移植：选择正确患者_Mariell.pptVIP

This table shows the percentage of patients experiencing various morbidities as reported within 5 years and within 10 years following transplantation. The percentages are based on patients with known responses. To reduce bias, only patients with responses reported on every follow-up through the 5-year annual (or 10-year annual) follow-up were included. Because the outcomes are reported to be unknown at different rates the number with known responses for each outcome are also provided. * * * * * * Slide 18 In 325 patients presenting to the ED with dyspnea, BNP levels were determined. Patients were then followed for 6 months looking for the following endpoints: death (cardiac and non-cardiac), hospital admissions (cardiac), and repeat ED visits for CHF. Using Kaplan-Meyer plots for all CHF events, patients who left the emergency department with BNP levels 480 pg/ml had a 6-month cumulative probability of a CHF event of (43%). On the other hand, patients who left the emergency department with BNP levels 230 pg/ml had an excellent prognosis with only 2.5% incidence of CHF end-points. The odds ratio for 6-month CHF death in patients with BNP levels 230 was 46. BNP levels measured in patients presenting with dyspnea to the ED are highly predictive of future cardiac events. Utilization of BNP levels in patients presenting with symptoms of CHF should prove to be a cost-effective way to risk-stratify patients with HF.  * * The age distribution of heart transplant recipients was compared between the eras using a chi-square test. Survival was calculated using the Kaplan-Meier method, which incorporates information from all transplants for whom any follow-up has been provided. Since many patients are still alive and some patients have been lost to follow-up, the survival rates are estimates rather than exact rates because the time of death is not known for all patients. Therefore, 95% confidence limits are provided about the survival rate estimate; the survival rate