血清opn try-2 ca199 ca125与胰腺癌的相关性分析-correlation analysis between serum opn try - 2 ca 199 ca 125 and pancreatic cancer.docxVIP
- 1、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。。
- 2、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 4、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 5、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
血清opn try-2 ca199 ca125与胰腺癌的相关性分析-correlation analysis between serum opn try - 2 ca 199 ca 125 and pancreatic cancer
床分期I期:35.65±8.95,8.14±1.55,185.48±23.26,36.78±2.52;临床分期II期:49.72±7.25,10.18±2.06,143.62±62.92,48.92±3.65;临床分期III期:59.95±9.78,14.42±3.32,288.45±71.18,60.75±8.52;临床分期IV期:70.42±6.58,18.95±4.18,326.58±80.85,71.45±10.61;组间比较差异具有统计学意义,P均0.05);合并淋巴结转移者上述指标均明显高于无淋巴结转移者(合并淋巴结转移者:68.44±11.95,17.96±4.21,295.76±81.52,69.15±9.78;无淋巴结转移者:41.48±9.52,10.44±3.62,195.85±43.65,35.46±2.25;t=6.54,5.22,83.88,11.66,P0.05)。Spearman秩相关分析法分析结果显示,胰腺癌患者血清OPN、Try-2、CA199、CA125水平与其临床分期呈正相关(r=0.792,0.765,0.743,0.755,P0.05),淋巴结转移也均呈正相关(r=0.765,0.778,0.751,0.749,P0.05)。结论:?血清OPN、Try-2、CA199、CA125在胰腺癌患者血清中显著增高。?血清OPN、Try-2、CA199、CA125水平检测均对诊断胰腺癌具有一定价值,联合四者水平检测,对胰腺癌诊断的特异性和敏感性高,误诊率和漏诊率较低,具有较高临床价值。?血清OPN、Try-2、CA199、CA125水平均与胰腺癌的临床病理特征相关,提示四者对预测胰腺癌病情程度具有重要的意义。【关键词】胰腺癌;骨桥蛋白;人胰蛋白酶原2;癌抗原199;癌抗原125IIIRelationshipbetweenserumOPN,Try-2、CA199、CA125andpancreaticcancerMajor:surgery(general)Postgraduate:YangPengSupervisor:SunChengyiZhaoJianyong[Abstract]Objective:ToinvestigaterelationshipbetweenOsteopontin(OPN),trypsinogen2(Try-2),cancerantigen199(CA199)andcancerantigen125(CA125)withpancreaticcancerthroughdetectingtheirserumexpressionlevel.Methods:30pancreaticcancerpatientsand30healthypersonswhohadphysicalcheck-upinhepticbilesurgerydepartmentofattachedhospitalofGuiyangmedicalcollegefromMarch,2013toOctober,2014wererandomlyselectedastheobjective.30healthypersonswithpersonnelphysicalexaminationwastakenashealthgroupand30patientswithpancreaticcancerweretakenasillgroup.Enzyme-linkedimmunosorbentassay(ELISA)methodwasappliedindetectingofserumOPN,Try-2,CA199andCA125levels.ValueofserumOPN,Try-2,CA199andCA125leveldiagnosingpancreaticcancerandClinicalpathologicalcharacteristicsofpatientswereanalyzedandSpearmanmethodwasappliedinanalysisoftherelationshipbetweenserumOPN,Try-2,CA199andCA125levelswiththeclinicalpathologicalcharacteristicsofpancreaticpatients.Results:(1)SerumOPN,Try-2,CA199andCA125levelsofillgroupweresignificantlyhigherthanthatofthehealthygroup,anddifferenceofserumOPN,Try-2,CA199andCA125levelsoftwogroupswasstatis
您可能关注的文档
- 雄激素经igf-i介导调节运动骨骼肌mtor信号机理的探索-exploration on the mechanism of androgen regulating mtor signal of exercise skeletal muscle via igf - i mediation.docx
- 雄性半滑舌鳎ghigf-i轴相关基因snp和dna甲基化与生长的相关性研究-correlation between growth and snp and dna methylation of ghi gf - i axis related genes in male cynoglossus semilaevis.docx
- 雄性黑腹果蝇抑制种间求偶生物学机制-biological mechanism of male drosophila melanogaster inhibiting interspecific courtship.docx
- 锈毛莓化学成分及药效学分析-analysis of chemical constituents and pharmacodynamics of cranberry.docx
- 锈色粒肩天牛寄主选择机制初步分析-preliminary analysis on host selection mechanism of monochamus alternatus.docx
- 锈蚀h型钢构件偏心受压性能分析-analysis of eccentric compression behavior of corroded h - section steel members.docx
- 锈蚀h型钢构件受弯承载性能分析-analysis of flexural bearing capacity of corroded h - section steel members.docx
- 锈蚀钢骨混凝土抗弯性能分析-analysis of flexural behavior of corroded steel reinforced concrete.docx
- 锈蚀箍筋约束混凝土单轴受压本构关系试验分析-experimental analysis on constitutive relation of corroded stirrups confined concrete under uniaxial compression.docx
- 锈蚀钢筋混凝土构件抗扭承载力分析-analysis of torsional bearing capacity of corroded reinforced concrete members.docx
- 血清ptx3与子痫前期及肾功能损害的相关性分析-correlation analysis of serum ptx 3 with preeclampsia and renal damage.docx
- 血清p hcg ca125检测在先兆流产中的临床应用-clinical application of serum p hcg ca 125 detection in threatened abortion.docx
- 血清saa crp在冠心病及冠心病合并糖尿病患者中的作用-role of serum saa crp in patients with coronary heart disease and coronary heart disease complicated with diabetes mellitus.docx
- 血清scc-ag对宫颈鳞癌新辅助化疗疗效早期评估的合理应用-reasonable application of serum scc - ag in early evaluation of neoadjuvant chemotherapy for cervical squamous cell carcinoma.docx
- 血清scd25测定在肝细胞癌诊断中意义-significance of serum scd 25 in diagnosis of hepatocellular carcinoma.docx
- 血清tat-2,vegf及il-6联合检测对胆管癌的早期诊断价值分析-value of serum tat - 2, vegf and il - 6 in early diagnosis of cholangiocarcinoma.docx
- 血清sp-d水平与2型糖尿病的相关性-correlation between serum sp - d level and type 2 diabetes mellitus.docx
- 血清tghdl-c比值与冠心病的相关性研究-correlation between serum tg hdl - c ratio and coronary heart disease.docx
- 血清tgf-β1和endoglin在成人急性淋巴细胞白`血病中的表达及其意义-expression and significance of serum tgf - β 1 and endo glin in adult acute lymphocytic leukemia.docx
- 血清tghdlc比值与冠心病的相关性研究-correlation between serum tg hdlc ratio and coronary heart disease.docx
文档评论(0)