t1加权mr体数据脑提取分析与实现-analysis and implementation of brain extraction from t1 weighted mr volume data.docxVIP

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t1加权mr体数据脑提取分析与实现-analysis and implementation of brain extraction from t1 weighted mr volume data.docx

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t1加权mr体数据脑提取分析与实现-analysis and implementation of brain extraction from t1 weighted mr volume data

AbstractAtpresent,researchonhumanbrainhasbecomeoneofthescientifichotspotsbecausescientistscanwidelystudyhumanbrainwithouthumandamagesowingtothemedicalimaging’simprovement.Therearemanyapplications(forexamplebrainvisualization,braindiagnoseetc)relatedtobrainimagingwhicheitherrequire,orbenefitfrom,theabilitytoaccuratelysegmentbrainfrombrainimagewhichincludeslotsofnon-braintissue,suchasskull,scalp,eyeballs.Therefore,brainextractionisthekeyofthehumanbrainresearch,andthefoundationofthefollowingbrainresearch.Fortherequestoffastandprecisioninbrainextraction,astrategyisputforwardinthispaperthatbrainisextractedtwiceautomated.Firstbrainextractionmethodisbasedondeformablesurfacemodelsaccordingtoglobalunderstandingoftheimageaftercomparedwithothermedicalimagesegmentationmethods.Firstlythedifferenceofintensityofdifferenttissueisenlargedthroughintensityhistogramprocessingaccordingtobrainanatomicandimagingknowledge,andthedistributionofbraintissueinintensityhistogram.Secondlythebrainsurfaceismodeledbyasurfacetessellationusingconnectedtrianglesandthesurfacemodelisallowedtoslowlydeform,onevertexatatime,followingforcesthatkeepthesurfacewell-spacedandsmooth,whilstattemptingtomovetowardsthebrain’sedge.Thirdlythevertexisstoppedbytriangleself-intersecting.Finallybrainextractionisfinishedbyregiongrowing.Secondbrainextractionmethodisbasedonmathematicalmorphologyaccordingtosemi-globalunderstandingoftheimage,withtheobjectofvoxel.ForthecharacterofT1weightedMRvolumetricdata,a3Dstructureelement6neighborsisapplied.Firstlyvolumetricdataismadeintodifferentregions.Thendifferentregionsareerodedintodifferentdegree.Finallymathematicalmorphologyachievesamoreprecisionbrainextraction.Atthesametimemathematicalmorphologyismadeuseofin3Dimagesegmentation.Brianextractionisaccomplished.ThenbrainextractionmethodsareII-evaluatedandtheparametersareestimatedbytheevaluationlawofimagessegmentation.Itisprovedthatbrainextractionbasedondeformablesurfacemodelshasprecisionmorethan92%,andbrainextractionofmathematicalmorpholo