抗生素的选择与使用（英文PPT）AntibioticSelection .pptVIP

Testing Urine Isn’t Tough …(Pre-Harvest Antibiotic Screening Test) * PHAST (B. meg. FAST used on urine) * * B. stearothermophilus DSM PremiTest, Charm KIS, 147?F (64 ?C) for 3 hrs * * * All positive screening tests are confirmed by approved analytical methods in an FSIS laboratory * What is the most important position our profession industry can have? DON’T SEND CATTLE TO MARKET WITH A RESIDUE! * * In the world of food Consumers Purchase BUY WHAT THEY TRUST * * * * * * * * * * * Finding Sick Cattle … Number one rule: ...Have plenty of timeearly every morning........If the temperature is going to be over 70-80 F that day ...... Be finished by 10AM RELOOK AT CATTLE OFTEN how to select a proper antibiotic for different diseases … will focus on BRD Pneumonia … Ab penetration not as much of a problem early as late Bugs that live in cells … need Ab that crosses cell walls Animal’s that are over whelmed can’t help the drug by fighting back … cidal Ab may be better than static Ab Can’t defend the use of Pen G (especially LA Pen) Sulfa in BRD Rx programs CAUTION – Generics … AVOID Bathtub mixes Neomycin Gentamicin … violate BQA reason how to know when to switch 1st … and very important … assess the “stress” effect of the Ab gut fill, soreness, tissue temp, etc don’t switch because of stress effect Monitor animal NOT temp!!! Don’t let the thermometer do your thinking Use temp to confirm your visual assessment Give the Ab 48 hours … @ MIC 90 which antibiotic would make a better choice when you need to switch … poor response Re-check the diagnosis … evaluate the treatment extras being used Use previous lab work … animals that die may be the most valuable If the infection is winning … get meaner Cidal Ab KILL bugs … good selection Ab that penetrate … good selection Ab that minimizes stress effect … may be good Have faith in the treatment plan … stick to it ! Letting go Giving up on a sick animal that has fail