精品PPT课件Pediatric Influenza Disease Lessons Learned From a Recent .pptVIP

Pediatric Influenza Disease: Lessons Learned From a Recent Pandemic Martha L. Muller, MD Assistant Professor, Department of Pediatrics University of New Mexico Health Sciences Center Talk Objectives To discuss epidemiology of seasonal and 2009 H1N1 influenza in pediatrics Nationwide University of New Mexico Children’s Medical Center To discuss clinical manifestations of seasonal and 2009 H1N1 influenza disease in pediatrics To discuss the relevance of bacterial co-infections in pediatric patients with influenza disease To discuss the difficulties we encountered with treatment and prevention of disease in our population Purpose So why bother with continued surveillance? Per CDC Flu activity, caused by either 2009 H1N1 or seasonal flu viruses, may rise and fall, but it is expected to continue for several more months. /h1n1flu/ Further, animal studies have suggested that 2009 H1N1 viruses are more pathogenic than seasonal H1N1 viruses Ann Saudi Med 2010; 30:1-10 Pediatric Influenza Epidemiology Significant pediatric respiratory virus Greatest morbidity and hospitalization rates in younger ages Community epidemics are sustained by high infection rates in preschool and school-aged children Pediatric 2009 H1N1 Epidemiology Initial cases in United States noted in children 15th and 17th April 2009 noted 2 children in California to have infection More important influenza ‘stats’ in the world of pediatrics Epidemiology that translates directly into the clinical forum: Secondary household attack rates thought to be approximately 27.3% In school settings, infected children predicted to infect 2.4 other children Children may be contagious longer Ann Saudi Med 2010; 30:1-10 Clinical manifestations Influenza illness in pediatrics Infant/toddler versus child ≥ 5 years old Traditional symptoms Acute otitis media Bronchiolitis Laryngotracheobronchitis Encephalopathy Clinical manifestations Influenza illness in pediatrics Infant/toddler versus child ≥