Signal-4-临床五年制2014PPT.ppt

Summary The overview of signal transduction Sigal molecules Receptor Signal transduction pathway Signal transduction and medical science Effect by membrane receptors Effect by intracellular receptors Intracellular molecules Extracellular molecules Signal molecules Second messengers: cAMP,IP3, Ca2+ Proteins: Enzymes, regulators, TFs Third messengers: DNA binding proteins Proteins and peptides: Hormones, cytokines Amino acid derivatives: Catecholamines(儿茶酚胺) Fatty acid derivatives: Prostaglandins Steroid hormones, Thyroxine, VD3 Gases: NO,CO Summary （1）Ion channel-linke