抗抑郁药物对全膝关节表面置换术后患者近期疗效的影响毕业答辩PPT.pptxVIP

抗抑郁药物对全膝关节表面置换术后患者近期疗效的影响研究背景材料与方法结果讨论研究背景骨关节炎以承重的膝关节多发，约占全部骨关节炎患者的35%[1]。膝关节骨关节炎终身患病率女性为47%，男性为40%[2]。除疼痛和畸形外，还可导致继发性肥胖、骨质疏松和心血管疾病等[3]。[1]de Rooij M, van der Leeden M, Avezaat E, et al. Development of comorbidity-adapted exercise protocols for patients with knee osteoarthritis. Clin Interv Aging. 2014. 9: 829-42.[2]Losina E, Weinstein AM, Reichmann WM, et al. Lifetime risk and age at diagnosis of symptomatic knee osteoarthritis in the US. Arthritis Care Res (Hoboken). 2013. 65(5): 703-11.[3]Mesci E, Icagasioglu A, Mesci N, Turgut ST. Relation of physical activity level with quality of life, s