免疫学课件-抗感染免疫PPT.pptVIP

G G G G o o o o M M M M o b o b o b o b G G G G o o o o M M M M o b o b o b o b G G G G o o o o M M M M a a a a c c c c d d d d a a a a c c c c d d d d x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x N-乙酰葡萄糖胺 β-1,4糖苷键 N-乙酰胞壁酸 四肽侧链 甘氨酸五肽 (五肽交联桥) 金黄色葡萄球菌细胞壁肽聚糖结构示意图 溶菌酶作用点 聚糖骨架 Principal leukocytes fibroblasts lymphocytes cell source NK cell IFN inducers dsRNA dsRNA mitogens virus virus or antigen Antiviral infection ++ ++ + Anti-tumor + + ++ Immunoregulation + + ++ Property IFN-? IFN- ? IFN- ? Interferon (IFN) ⑴ definition 干扰素是由病毒或其他干扰素诱生剂刺激机体多种细胞所产生的一种具有抗病毒、抗肿瘤和免疫调节等多种生物学活性的糖蛋白 ⑵ types and properties binds to surface receptor of neighboring cells ⑶ Mechanism of antiviral activity the synthesis of antiviral protein(AVP) induce