寡转移脑术后治疗选择2017-11-8PPT.ppt

结果：1、脑转移复发 WBRT SRS P Local Recurrence rate 34/92 (37%) 66/93 (70%) 0.001 Median time of local BM recurrence 27.5M 6.4M 0.0001 6-month surgical bed control 87.1% 80.4% 0.00068 SRS在颅内无论是局部瘤床或是远处控制均显著差于WBRT 脑膜转移发生率两组无明显差异 2、生存分析 WBRT SRS P OS 11.6M 12.2M 0.70 SRS对比WBRT在生存方面无显著差异 3、行为认知能力 WBRT SRS P Cognitive-deterioration free survival  3.0M 3.7M 0.001 Functional independce Better decline 3M 1/66(2%) 8/66(12%) 8/70(10%) 4/70(5%) 0.036 Functional independce Better decline 6M 1/48(2%) 7/48(15%) 5/60(8%) 3/60(5%) 0.10 Median duration of stable or better functionalindependence  1