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New Metho ds of Time Series Analysis
of Non-Stationary EEG Data:
Eigenstructure Decomp ositions of
Time Varying Autoregressions
Andrew D. Krystal, Raquel Prado and Mike West
May 31, 1999
Andrew Krystal is Assistant Professor in the Department of Psychiatry and Behavioral
Sciences and Director of the Quantitative EEG Lab oratory at Duke University Medical
Center, Durham NC 27710, USA. Raquel Prado is Assistant Professor, Departamento de
Computo Cient co y Estad stica, Universidad Simon Bol v ar, Caracas, Venezuela. Mike
West is Arts Sciences Professor of Statistics and Decision Sciences, and Director of
the Institute of Statistics and Decision Sciences, Duke University, Durham, NC 27708-
0251, USA. The work rep orted here was carried out in the Department of Psychiatry
and the Institute of Statistics and Decision Sciences at Duke University. The authors
acknowledge partial nancial supp ort under grants NIMH K20MH01151, R29MH57532
and NSF/DMS-9704432. Address for corresp ondence: Dr. A. D. Krystal, Box 3309, Duke
University Medical Center, Durham NC 27710. tel: (919) 681-8742, fax: (919) 681-8744.
0
Abstract
OBJECTIVE: Those who analyze EEG data require quantitative tech-
niques that can b e validly applied to time series exhibiting ranges of
non-stationary b ehavior. Our ob jective is to intro duce a new analysis
technique based on formal non-stationary time series mo dels. This
novel metho d provides a decomp osition of the time series into a set of
\latent comp onents with time-varying frequency content. The identi-
cation of these comp onents can lead to practical
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