2010补体PPT课件.pptVIP

Complement Jules Bordet (1870-1961), Discoverer of complement Discoverer of complement 不溶菌 溶菌 muddy clear Complement refers to fresh serum capable of lysing antibody (Ab)-coated cells. This activity is destroyed (inactivated) by heating serum at 56 ℃ for 30 minutes. 补体（complement） 广泛存在于血清、组织液和细胞膜表面的一组经活化具有酶活性的蛋白质，是一个具有精密调控机制的蛋白质反应系统。 - Complement system consists of approximately 30 serum molecules include soluble and membrane binding proteins. 补体系统：由30余种可溶性蛋白质和膜结合蛋白组成的多分子系统，具有酶的活性和自我调节作用。 Complement system Nomenclature of complement C1(q, r, s), C2, …C9 factor B, factor P, factor H Comp