青岛大学基础医学院医学免疫学课件 chapter11.pptVIP

Chapter 11 Cells of adaptive immune response :B lymphocytes INTRODUCTION origin:bone marrow basic function: humoral immune response Section 1 membranous molecules on B lymphocyte and functions 一、B cell receptor ，BCR Constitution of BCR complex： mIg（IgM and IgD）and Ig?（CD79a）/Ig ?（CD79b） 1、mIg Structure：mIg consist of a basic unit of four polypeptide chains,two identical H chains and two identical L chains. Intracellular region is very short. immature B cells express mIgM， mature B cells express mIgM and mIgD simultaneously，plasma cells don’t express Ig. Function：specific binding anti