Stem Cells - Winston-SalemForsyth County Schools：干细胞-温斯顿salemforsyth县学校.pptVIP

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Stem Cells - Winston-SalemForsyth County Schools：干细胞-温斯顿salemforsyth县学校.ppt

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Stem Cells - Winston-SalemForsyth County Schools：干细胞-温斯顿salemforsyth县学校

STEM CELLS REMARKABLE REGENERATION! CAN HUMANS REGENERATE BODY PARTS? CAN HUMANS REGENERATE BODY PARTS? Some stem cells are different than others! Stem cells vary in what they can become. Some stem cells can only become one type of cell, other stem cells can generate an entire organism! STEM CELLS Potency Totipotent Pluripotent Multipotent Unipotent STEM CELLS Potency Totipotent Pluripotent Multipotent Unipotent STEM CELLS Potency Totipotent: a stem cell that has the ability to divide and produce all the differentiated cells in an organism, including the placenta. A totipotent stem cell can generate an ENTIRE organism! Example: cell from morula stage of embryo STEM CELLS Potency Totipotent Pluripotent Multipotent Unipotent STEM CELLS Potency Pluripotent: a stem cell that has the ability to divide and differentiate into any fetal or adult cell type (but not the placenta). Thus, a pluripotent stem cell can differentiate into any cell type but cannot become a new organism. Example: cell from inner cell mass of blastocyst STEM CELLS Potency Totipotent Pluripotent Multipotent Unipotent STEM CELLS Potency Multipotent: a stem cell that has the ability to divide and differentiate into cells of a limited range of types. Example: Blood stem cell (hematopoietic cell) STEM CELLS Potency Totipotent Pluripotent Multipotent Unipotent STEM CELLS Potency Unipotent: a stem cell that has the ability to divide and differentiate into only one type of cell. Example: Skin stem cells STEM CELLS So, what IS a stem cell? STEM CELLS STEM CELLS So, what IS a stem cell? Two defining characteristics… Self-renewal: Retain the capacity to go through many cycles of cell division while remaining undifferentiated. Potency: Ability to differentiate STEM CELLS So, what IS a stem cell? A stem cell is a cell that has the ability to self-renew and differentiate along different pathways. STEM CELLS EMBRYONIC STEM CELLS VS. ADULT STEM CELLS Embryonic stem cell: stem cell derived from the inner cell mass