某院中药注射不良反应分析.docVIP

某院中药注射剂不良反应分析 　　[摘要] 目的 分析医院中药注射剂不良反应情况，探讨减少中药注射剂不良反应的方法。 方法 从广东省药品不良反应管理平台收集2014年1月～2015年11月本院中药注射剂的不良反应报告资料，分析中药注射剂不良反应发生的时间分布、年龄分布、涉及的器官和临床症状以及发生不良反应的中药注射剂品种。 结果 2014年的中药注射剂不良反应发生率为0.26%，2015年的中药注射剂不良反应发生率为0.15%。注射10～30 min内的不良反应发生率为57.0%，30 min～1 h内的不良反应发生率为24.4%。50岁以上人群的不良反应发生率为62.8%。不良反应涉及的器官主要是皮肤及其附件，临床主要症状为皮疹、瘙痒。活血化瘀类和清热解毒类中药注射剂易发生不良反应。 结论 中药注射剂不良反应的发生与时间和年龄相关，不良反应涉及多个器官，临床症状多样，活血化瘀类和清热解毒类中药注射剂易发生不良反应。 中国论文网 /6/viewhtm　　[关键词] 中药注射剂；不良反应；分析 　　[中图分类号] R969.3 [文献标识码] A [文章编号] 1674-4721（2016）03（c）-0100-03 　　[Abstract] Objective To analysis the adverse reaction of traditional Chinese medicine injection，and to explore a effective method to promote rational use of traditional Chinese medicine injection. Methods The adverse reaction reports of traditional Chinese medicine injection from January 2014 to November 2015 were collected from Guangdong province drug adverse reaction monitoring platform to analysis the age distribution，time distribution，clinical symptom and varieties of the traditional Chinese medicine injection which caused adverse reaction. Results The incidence rate of adverse reaction of traditional Chinese medicine injection in 2014 was 0.36%，which was 0.15% in 2015.There was happened 57.0% adverse reactions in 10-30 min when started getting the injection，and 24.4% was happened in 30 min-1 h.The incidence rate of adverse reaction of traditional Chinese medicine injection over 50 years old people was 62.8%.The major organ damaged by adverse reaction of traditional Chinese medicine injection were skin and its accessories.The main clinical manifestation were rash and pruritus.The adverse reaction was caused by the traditional Chinese medicine injection that promoting blood circulation for removing blood stasis or clearing away heat and toxic material. Conclusion The incidence rate of adverse reaction of traditional Chinese medicine injection is closely related to age and injection time.The adverse reaction involve multiple organs with various c