利尿剂对老年高血压患者血压血钾尿酸及三酰甘油影响.docVIP

利尿剂对老年高血压患者血压血钾尿酸及三酰甘油影响 　　[摘要] 目的 探究利尿剂对老年高血压患者血压、血钾、尿酸及三酰甘油的影响，为该病临床治疗积累相关实践性经验。 方法 选取本院心内科于2010年1月~2012年12月收治的102例高血压患者，根据服用降压药物的不同进行分组，分为利尿剂组（50例）和非利尿剂组（52例）。同时选取同期来院门诊或复查的老年高血压者（未服用降压药或自行停药1个月以上者），设为对照组。 结果 3组的血压、体质指数、肌酐、TC、HDL-C、LDL-C和LVEF差异无统计学意义（P0.05）；利尿剂组、非利尿剂组的收缩压、舒张压均低于对照组（P 　　[关键词] 高血压；利尿剂；非利尿剂；生化指标 　　[中图分类号] R544.1[文献标识码] A[文章编号] 1674-4721（2014）05（b）-0077-04 　　 　　The influence of diuretic on blood pressure,serum potassium,uric acid and triacylglycerol in elderly patients with hypertension 　　JIA Jing-tao 　　Department of Cardiology,the Ninth People′s Hospital of Nanyang City in Henan Province,Nanyang 473065,China 　　[Abstract] Objective To explore the influence of diuretic on blood pressure,blood potassium, uric acid and triacylglycerol in elderly patients with hypertensive,and accumulating related practical experience of the clinical treatment of disease. Methods 102 cases with hypertension in department of cardiology in our hospital from January 2010 to December 2012 were selected and divided into the diuretic group (n=50) and the non diuretic group (n=52) according the different of antihypertensive drugs applied.At the same time,the elderly patients with hypertension (not taking antihypertensive drugs or to stop the drug on their own for more than 1 month) were selected as the control group. Results There was no statistical difference of blood pressure,body mass index,creatinine,TC,HDL-C,LDL-C and LVEF among the three groups (P0.05);systolic and diastolic blood pressure in the diuretic group and the non diuretic group were lower than those in the control group (P 　　1 资料与方法 　　1.1 一般资料 　　选取本院心内科于2010年1月~2012年12月收治的102例高血压患者，其中男性62例，女性40例，年龄66~82岁，平均（71.6±2.3）岁。所有患者入院当天均常规测量血压，若收缩压＞140 mm Hg和（或）舒张压＞90 mm Hg，则为高血压，诊断参??人民卫生出版社第7版《内科学》教材中关于该病的诊断标准。纳入标准：患者收缩压＞150 mm Hg和（或）舒张压95 mm Hg，或正在服用降压药者。排除标准：患者存在痛风、血清肌酐150 μmol/L者、心功能（NYHA）Ⅳ级或LVEF0.05）（表1）。 　　 　　表1 3组患者各项指标的比较（x±s） 　　 　　 　　 　　 　　 　　 　　2.2 3组患者血压、血钾、尿酸及三酰甘油的比较 　　利尿剂组、非利尿剂组的收缩压和舒张压均