【高血压英文ppt课件】高血压的运动治疗 Therapeutic role of exercise in treating hypertension.pptVIP

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【高血压英文ppt课件】高血压的运动治疗 Therapeutic role of exercise in treating hypertension.ppt

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【高血压英文ppt课件】高血压的运动治疗 Therapeutic role of exercise in treating hypertension

Preliminary Results Outcome measures analyzed at beginning of study, week 0 (t0) end of intervention period, week 12 (t1) end of maintenance period, week 24 (t2) Change in Systolic BP from Time 0 to Time 1 (12 weeks) for both groups P = .005 Change in Systolic BP across time for both groups (24 weeks) Change in Diastolic BP from Time 0 to Time 1 for both groups (12 weeks) Change in Diastolic BP across time for both groups (24 weeks) Change in BMI across time for both groups (24 weeks) Change in PASE across time for both groups (24 weeks) Preliminary Conclusions Intervention alone (Group 1) did not significantly improve BP Intervention plus a pedometer (Group 2) significantly improved BP, but only with regular physician visits Possible Mechanisms of BP Reduction with Exercise Reduced visceral fat independent of changes in body weight or BMI Altered renal function to increase elimination of sodium leading to reduce fluid volume Anthropomorphic parameters may not be primary mechansims in causing HTN Possible Mechanisms of BP Reduction with Exercise Lower cardiac output and peripheral vascular resistance at rest and submaximal exercise Decreased HR Decreased sympathetic and increased parasympathetic tone Lower blood catecholamines and plasma renin activity Antihypertensive Volume Depleting Effects of Mild Exercise on Essential HTN 20 subjects with HTN (155/100) randomized to Exercise or Control group Cycle Ergometer Exercise at Blood Lactic Acid Threshold for 60 min. 3X/wk for 10 weeks Changes in BP, hemodynamics and humoral factors of EX group compared with control group Urata, H., et. al. Hypertension 9:245-252,1987 Antihypertensive Volume Depleting Effects of Mild Exercise on Essential HTN Antihypertensive Volume Depleting Effects of Mild Exercise on Essential HTN Whole blood and plasma volume indices were significantly reduced (p 0.05) Change in serum Na+:serum K+ positively correlated with change in SBP Plasma NE concentrations at rest Workload @ BLAT