药理学ppt课件16 抗癫痫药及抗惊厥药.pptVIP

第16章 抗癫药及抗惊厥药  Chapter 16  Antiepileptic and Anticonvulsant;The characteristic event of epilepsy is the seizure(often associated with a convulsion), which is caused by abnormal high-frequency discharge of some group of neurons, starting locally and spreading to a varying extent to affect other part of the brain. Current drug therapy is effective in 70%~80% of patients.; 多种病因引起的长期反复发作性的大脑功能失调。其特征为发作时大脑局部病灶神经元突发性的异常高频放电并向周围组织扩散，出现短暂的大脑功能失调。表现为突然发作性的短暂的运动、感觉、意识和植物神经功能异常,可伴有脑电图改变。癫的治疗应长期用药，以减少或防止发作，但不能根治。;Table 16-1 (1) Types of Epilepsy and Anti-epileptic Drugs;Ta