《细胞过继免疫治疗肿瘤的临床研究进展》ppt课件.pptVIP

细胞过继免疫治疗肿瘤的临床研究进展;细胞免疫治疗肿瘤的发展;国内细胞免疫治疗研究热潮;肿瘤的细胞免疫治疗 经过体外培养加工;CIK Cytokine induced killer;2009，Germany，Prof. Dr. Schmidt-Wolf 建立了CIK临床研究登记网站 ，目前收集发表的文章39篇，中国人发表26篇(占2/3)。 2011，J Cancer Res Clin Oncol. “Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)”. PubMed the keywords ‘‘CIK cells clinical trials’’，evaluated 11 studies（426人）. 并与作者联系核实 涉及的杂志：Digestive and Liver Disease, Chinese Journal of Cancer, Anticancer Research, World Journal of Gastroenterology , Haematologica, British Journal of Cancer, Biology of Blood, and Marrow Transplantation. In some studies, abstracts were only available in Chinese. Unfortunately, these studies are often published only in Chinese. international standard ;Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC);Table 1 Tumor entity with number of respective patients, male-to-female ratio, andtherapeutic effects;Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors Dario Sangiolo, Italy Journal of Cancer 2011; 2: 363-36 ;Fig. 1. Disease-free survival curves of the three groups. Kaplan–Meier was employed to estimate the disease-free survival rates of the three groups. Logrank test shows a significantly higher rates in the CIK-I group (p = 0.001) and the CIK-II group (p = 0.004) than in the control group. No statistical significance was found between the CIK-I group and the CIK-II group (p = 0.345).;;A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma;Figure 1 Survival rates of patients after cytokine-induced killer cells immunotherapy plus chemotherapy and chemotherapy alone. CIK: Cytokineinduced killer.;World J Gastroenterol 2010 December 28; 16(48): 6155-6162 Jing-Ting Jiang, Yue-Ping Shen, Chang-Ping Wu, Yi-Bei Zhu, Wen-Xiang Wei, Lu-Jun Chen, Xiao Zheng,Jing Sun, Bin-Feng Lu, Xue-Guang Zhang 苏州大学;Cord blood-derived cytokine-induced