生物芯片和纳米中药对肝胆肿瘤早期诊治的分析-analysis of biochip and nano-traditional chinese medicine in early diagnosis and treatment of hepatobiliary tumors.docx

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生物芯片和纳米中药对肝胆肿瘤早期诊治的分析-analysis of biochip and nano-traditional chinese medicine in early diagnosis and treatment of hepatobiliary tumors.docx

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生物芯片和纳米中药对肝胆肿瘤早期诊治的分析-analysis of biochip and nano-traditional chinese medicine in early diagnosis and treatment of hepatobiliary tumors

独创性声明本人郑重声明，本学位论文是本人在导师指导下进行的研究工作及取得的研究成果的总结。尽我所知，除文中已经标明引用的内容外，本论文不包含任何其他个人或集体已经发表或撰写过的研究成果。对本文的研究做出贡献的个人和集体，均已在文中以明确方式标明。本人完全意识到本人将承担本声明引起的一切法律后果。学位论文作者签名：日期：年月日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定，即：学校有权保留并向国家有关部门或机构送交论文的复印件和电子版，允许论文被查阅和借阅。本人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据库进行检索，可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。本论文属于保密□，在年解密后适用本授权书。不保密□。（请在以上方框内打“√”）学位论文作者签名：指导教师签名：日期：年月日日期：年月日目录主要略缩词一览表·······························································································1前言·······················································································································2中文摘要·················································································································4Abstract9本研究创新点······································································································16第一部分生物芯片早期诊断肝胆肿瘤的探讨···································17PartⅠMeDIP芯片分析和建立胆管癌差异甲基化谱17引言················································································································18材料和方法·····································································································19结果················································································································22讨论··············································································································28参考文献·········································································································29PartⅡ无透镜显微镜联合细胞诊断芯片集成系统的构建31前言················································································································31材料与方法·····································································································32结果················································································································35讨论················································································································37结论······················