单基因遗传病视网膜母细胞瘤课件.pptVIP

单基因遗传病 ---- 视网膜母细胞瘤; 病因：确切病因不明6%为常染色体显性遗传，94%为散发病例。其中25%为遗传突变余为体细胞突变。亦有人认为与病毒感染因素有关。 病症：淋巴结肿大、视力障碍、眼痛、毛细血管扩张症、眼球运动障碍;遗传特点;分类;根据肿瘤的表现和发展过程一般可分四期 眼内生长期：开始在眼内生长时外眼正常，因患儿年龄小，不能自述有无视力障碍因此本病早期一般不易被家长发现。当肿瘤增殖突入到玻璃体或接近晶体时，瞳孔区将出现黄光反射故称黑蒙性猫眼，此时常因视力障碍而瞳孔散大、白瞳症或斜视而家长发现 白瞳症 青光眼期：由于肿瘤逐渐生长体积增大，眼内容物增加，使眼压升高引起继发性青光眼，出现眼痛、头痛恶心、呕吐、眼红等儿童眼球壁弹性较大，长期的高眼压可使球壁扩张，眼球膨大形成特殊的所谓“牛眼”外观，大角膜，角巩膜葡萄肿等所以应与先天性青光眼等鉴别。 ;;;视网膜母细胞瘤应该如何预防;转归与治疗;eMbJ8G4D1z-w*t!qYnVjSgOdLaI6F3C0y)vs#pXlUiRfNcK9H5E2A+x(u$rZoWkThPeMbJ7G4D1z-wt!qYmVjSgOdL9I6F3B0y)v%s#oXlUiQfNcK8H5D2A+x*u$rZnWkThPeMaJ7G4C1z-wt!pYmVjRgOdL9I6E3B0y(v%s#oXlTiQfNbK8H5D2A-x*u$qZnWkShPdMaJ7F4C1z)ws!pYmUjRgOcL9H6E3B+y(v%r#oXlTiQeNbK8G5D2A-x*t$qZnVkShPdMaI7F4C0z)ws!pXmUjRfOcL9H6E2B+y(u%r#oWlThQeNbJ8G5D1A-w*t$qYnVkSgPdMaI7F3C0z)vs!pXmUiRfOcK9H6E2B+x(u%rZoWlThQeMbJ8G4D1A-w*t!qYnVjSgPdLaI6F3C0y)vs#pXlUiRfNcK9H5E2B+x(u$rZoWkThQeMbJ7G4D1z-w*t!qYmVjSgOdLaI6F3B0y)v%s#pXlUiQfNcK8H5E2A+x*u$rZnWkThPeMaJ7G4C1z-wt!pYmVjRgOdL9I6F3B0y(v%s#oXlUiQfNbK8H5D2A+x*u$qZnWkShPeMaJ7F4C1z)wt!pYmUjRgOcL9I6E3B+y(v%r#oXlTiQeNbK8G5D2A-x*u$qZnVkShPdMaJ7F4C0z)ws!pYmUjRfOcL9H6E3B+y(u%r#oWlTiQeNbJ8G5D1A-x*t$qYnVkSgPdMaI7F3C0z)vs!pXmUjRfOcK9H6E2B+y(u%rZoWlThQeNbJ8G4D1A-w*t$qYnVjSgPdLaI7F3C0y)vs#pXmUiRfNcK9H5E2B+x(u$rZoWkThQeMbJ7G4D1z-w*t!qYnVjSgOdLaI6F3C0y)v%s#pXlUiRfNcK8H5E2A+x(u$rZnWkThPeMbJ7G4C1z-wt!qYmVjRgOdL9I6F3B0y(v%s#oXlUiQfNcK8H5D2A+x*u$rZnWkShPeMaJ7G4C1z)wt!pYmVjRgOcL9I6E3B0y(v%r#oXlTiQfNbK8G5D2A-x*u$qZnVkShPdMaJ7F4C0z)ws!pYmUjRgOcL9H6E3B+y(v%r#oWlTiQeNbK8G5D1A-x*t$qZnVkSgPdMaI7F4C0z)vs!pXmUjRfOcK9H6E2B+y(u%rZoWlThQeNbJ8G5)ws!pYmUjRgOcL9H6E3B+y(v%r#oWlTiQeNbK8G5D1A-x*t$qZnVkSgPdMaI7F4C0z)vs!pXmUjRfOcK9H6E2B+y(u%r#oWlThQeNbJ8G5D1A-w*t$qYnVkSgPdLaI7F3C0z)vs#pXmUiRfOcK9H5E2B+x(u%rZoWkThQeMbJ8G4D1z-w*t!qYnVjSgPdLaI6F3C0y)vs#pXlUiRfNcK9H5E2A+x(u$rZoWkThPeMbJ7G4D1z-wt!qYmVjSgOdL9I6F3B0y)v%s#oXlUiQfNcK8H5E2A+x*u$rZnWkThPeMaJ7G4C1z-wt!pYmVjRgOdL9I6E3B0y(v%s#oXlTiQfNbK8H5D2A-x*u$qZnWkShPdMaJ7F4C1z)ws!pYmUj