CO2激光联合甘露聚糖肽注射液治疗尖锐湿疣临床研究.docVIP

CO2激光联合甘露聚糖肽注射液治疗尖锐湿疣临床研究 　　【摘要】目的：观察CO2激光联合甘露聚糖肽注射液治疗尖锐湿疣的临床疗效，以期为尖锐湿疣的治疗提供借鉴。方法：选取在2009年4月至2012年6月以来我院和济南市中心医院就诊的尖锐湿疣患者120例为研究对象，并随机分为两组，治疗组和对照组，对照组予以单纯CO2激光治疗，治疗组在CO2激光治疗的基础上合用甘露聚糖肽注射液静滴治疗。观察其治愈情况及预防复发的临床效果。结果：两组尖锐湿疣患者在性别、年龄和体重差别均无统计学意义（P0.05）。两组治愈率分别为83.87%、51.72%，进行卡方检验，χ2=7.493，P=0.0240.05，无显著差异。结论：CO2激光联合甘露聚糖肽注射液治疗尖锐湿疣的临床疗效，为尖锐湿疣的治疗提供借鉴，值得推广。 　　【关键词】 CO2激光联合甘露聚糖肽注射液；尖锐湿疣；临床研究 　　Clinical study of CO2 laser combined with Mannatide injection in the treatment of condyloma acuminatumCHENG Lei1， CHENG Hong2. 1. Dermatology Department， People’s Hospital of Linqing City， Liaocheng 252600， China； 2. Dermatology Department， Ji’nan Central Hospital Affiliated to Shandong University， Ji’nan 250000， China 　　【Abstract】Objectives： To investigate the clinical efficacy of CO2 laser combined mannatide injection in the treatment of genital warts in order to provide reference for the treatment of genital warts. Methods： 120 patients with genital warts in our hospital from April 2009 to June 2012 were selected and randomly divided into the treatment group and the control group. The control group was given CO2 laser treatment， while treatment group was given additional mannatide intravenous injection on the basis of CO2 laser treatment. The cure and prevention of relapse results were compared. Results： Differences in gender， age and weight between the two groups were not statistically significant （P0.05）. The cure rates of the two groups were 83.87% and 51.72%， （χ2=7.493， P=0.0240.05） without significant difference. Conclusions： CO2 laser combined with mannose glycans injection is of good clinical efficacy in the treatment of genital warts， providing reference for the treatment of genital warts， which is worthy of promotion. 　　【Key words】CO2 laser combined mannatide injection； Genital warts； Clinical study 　　【中图分类号】R 752.5+3【文献标志码】A 　　尖锐湿疣（Condyloma acuminatum，CA）是一种常见的性传播疾病，少数通过间接接触传染，常由人乳头状瘤病毒（human papillomaviros ， HPV）引起，表现为皮肤黏膜良性赘生物，严重者可引起生殖器癌。随着社会发展，性开放程度加大，尖锐湿疣亚临床感染