cTn―Ⅰhs―CRP及D―2聚体检测在急性胸痛患者急诊科危险分层应用研究.docVIP

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cTn―Ⅰhs―CRP及D―2聚体检测在急性胸痛患者急诊科危险分层应用研究.doc

cTn―Ⅰhs―CRP及D―2聚体检测在急性胸痛患者急诊科危险分层应用研究

cTn―Ⅰhs―CRP及D―2聚体检测在急性胸痛患者急诊科危险分层应用研究   【摘要】 目的:探讨心肌肌钙蛋白Ⅰ(cTn-I)、超敏C反应蛋白(hs-CRP)和D-2聚体(D-D)检测在急性胸痛患者急诊科危险分层的临床价值。方法:选择2014年9月-2015年9月因急性胸痛在笔者所在医院急诊科接受治疗的患者140例,将其分为研究组(ACS患者)63例和对照组(非ACS患者)77例,比较不同胸痛患者、不同时间的cTn-I、hs-CRP、D-D水平差异。结果:同组患者的cTn-I、hs-CRP、D-D水平均随时间的延长而增加,研究组患者的cTn-I、hs-CRP、D-D同期水平均明显高于对照组,差异均有统计学意义(P0.05)。结论:通过cTn-I、hs-CRP、D-D等多种标记物水平的检查,可以判定ACS不同的病理特征和病理阶段,对其危险分层和早期诊治有重大临床应用价值。   【关键词】 cTn-I; hs-CRP; D-2聚体; 急性胸痛; 危险分层   中图分类号 R541 文献标识码 B 文章编号 1674-6805(2016)22-0028-03   【Abstract】 Objective:To investigate the clinical value of cardiac troponin Ⅰ(cTn-I),high sensitive C reactive protein(hs-CRP) and D-2(D-D) in patients with acute chest pain.Method:140 patients with acute chest pain in the emergency department of the author’s hospital from September 2014 to September 2015 were selected,they were divided into the study group (ACS) in 63 cases,the control group (non ACS) in 77 cases,compared the differences of cTn-I,hs-CRP,and D-D levels in patients with different chest pain at different times.Result:The same group of patients with cTn-I,hs-CRP,D-D levels were increased with the time,the study group of patients with cTn-I,hs-CRP,D-D levels were significantly higher than those of the control group,the differences were statistically significant(P0.05).Conclusion:Through the cTn-I,hs-CRP,D-D and other markers of the level of inspection,you can determine the different pathological characteristics and pathological stage of ACS,the risk stratification and early diagnosis and treatment has significant clinical application value.   【Key words】 Cardiac troponin I; Hypersensitive C-reactive protein; D-D; Acute chest pain; Risk stratification   First-author’s address:The People’s Hospital of Longhua New District in Shenzhen,Shenzhen 518109,China   doi:10.14033/j.cnki.cfmr.2016.22.013   本文以联合检测心肌肌钙蛋白Ⅰ(cTn-I)、超敏C反应蛋白(hs-CRP)和D-2聚体(D-D)含量,探讨其对急诊胸痛患者早期危险度分层的临床价值,现报道如下。   1 资料与方法   1.1 一般资料   选择2014年9月-2015年9月因急性胸痛在笔者所在医院急诊科接受治疗的患者140例,胸痛发作时间在6 h内,排除以下患者:确诊为肺部疾病

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