不同剂量米索前列醇配伍盐酸丁卡因胶浆用于绝经后取环临床观察.docVIP

不同剂量的米索前列醇配伍盐酸丁卡因胶浆用于绝经后取环的临床观察 　　【第一作者简介】郭幼华(1963-)，女，主治医师，主要从事妇产科、计划生育临床及研究工作。 　　【摘要】目的:探讨绝经后取器手术中舌下含服米索前列醇的用量，缩短手术时间，降低药物副作用，达到松弛宫颈，减轻疼痛程度的目的，避免因IUD取出带来的机械损伤。方法:采用400μg和200μg两种不同剂量的米索前列醇舌下含服配伍盐酸丁卡因胶浆用于绝经1年以上，放置金属单环20年以上的农村妇女，观察两组术中宫口松弛、术中疼痛、术前阴道出血、腹坠痛及取器效果的情况。结果:A组用药剂量小，其松弛宫颈、镇痛及取器效果效果与B组无差异，术前阴道出血、腹痛等副反应明显低于B组P0??01。结论:将米索前列醇计量减少到200μg合并盐酸丁卡因胶浆用于绝经后取环，达到了常规用量松弛宫颈、镇痛的作用，其药物副反应小，取器成功率略高于常规用量。 　　【关键词】米索前列醇给药途径;盐酸丁卡因胶浆;绝经后取环;临床效果 　　Effect of different doses of misoprostol combining with tetracaine hydrochloride mortar in extraction of IUD for post-menopause womenGUO Youhua1, WANG Yanqing2, JANG Liqing3, HU Wenyun1, ZHANG Xiuyan1. 1. Family planning service stations of Funing County，Qinhuangdao, Hebei Province， 066300,China; 2. Galactophore Department, Maternal and Child Care Service Center of Qinhuangdao, Qinhuangdao 066000, China; 3. Department of Obstetrics and Gynecology, Maternal and Child Care Service Center of Funing County, Qinhuangdao 066300, China 　　【Abstract】Objectives: To investigate the amount of sublingual misoprostol keeping under tongue in extraction of IUD to shorten the surgery time, reduce side effects, relax cervix, relieve pain and avoid mechanical damage caused in the surgery. Methods: Two different doses, 400μg and 200μg, of sublingual misoprostol combined with tetracaine hydrochloride mortar were used in extraction of IUD placed over 20 years in rural women who were menopausal for over one year, to observe the situation of cervix relaxation, surgery pain, preoperative vaginal bleeding, abdominal pain and effect of both groups. Results: With small dose, the degree of relaxation of cervix, surgery pain and effect of group A was of no difference from group B. Preoperative vaginal bleeding, abdominal pain and other side effect of group A were significantly lower than group B, P0??01. Conclusion: Joint use of 200μg misoprostol and tetracaine hydrochloride mortar in extraction of IUD in post-menopause women can achieve the same effect in relax