中度哮喘给予小剂量布地奈德福莫特罗干粉吸入剂与茶碱缓释片联合治疗效果分析.docVIP

中度哮喘给予小剂量布地奈德福莫特罗干粉吸入剂与茶碱缓释片联合治疗的效果分析 　　【摘要】 目的 研究小剂量布地奈德福莫特罗干粉吸入剂联合茶碱缓释片治疗中度哮喘患者的临床效果。方法 58例中度哮喘患者， 依据入院时间先后将患者分为观察组和对照组， 各29例。对照组给予小剂量布地奈德福莫特罗干粉吸入剂联合酮替芬分散片治疗， 观察组给予小剂量布地奈德福莫特罗干粉吸入剂联合茶碱缓释片治疗， 比较两组治疗效果及肺功能情况。结果 观察组患者治疗总有效率为96.6%， 显著高于对照组的75.9%， 差异有统计学意义（P0.05）。治疗后观察组患者第一秒用力呼气容积（FEV1）、FEV1/用力肺活量的比值（FEV1%）明显优于对照组， 差异有统计学意义（P0.05）。结论 小剂量布地奈德福莫特罗干粉吸入剂联合茶碱缓释片治疗中度哮喘患者效果显著， 能有效控制患者病情并改善其肺功能指标， 值得临床推广。 　　【关键词】 中度哮喘；布地奈德福莫特罗干粉吸入剂；茶碱缓释片；酮替芬 　　DOI：10.14163/j.cnki.11-5547/r.2018.02.046 　　Effect analysis of low-dose budesonide formoterol powder inhalation combined with theophylline sustained-release tablets in the treatment of moderate asthma DIAO Zhen-hua， DUAN Cai-rao. Department of Respiratory Medicine， Shenzhen Longgang District Second People’s Hospital， Shenzhen 518112， China 　　【Abstract】 Objective To study the clinical effect of low-dose budesonide formoterol powder inhalation combined with theophylline sustained-release tablets in the treatment of patients with moderate asthma. 　　Methods A total of 58 patients with moderate asthma were divided by admission order into observation group and control group， with 29 cases in each group. The control group received low-dose budesonide formoterol powder inhalation combined with ketotefen dispersible tablet， and the observation group received low-dose budesonide formoterol powder inhalation combined with theophylline sustained-release tablets. Comparison were made on treatment efficacy and pulmonary function between two groups. Results The observation group had obviously higher total treatment effective rate as 96.6% than 75.9% in the control group， and the difference was statistically significant （P0.05）. After treatment， the observation group had obviously better forced expiratory volume in 　　1 second （FEV1）， FEV1 / forced vital capacity （FEV1%） than the control group， and their difference was statistically significant （P0.05）. Conclusion Low-dose budesonide formoterol powder inhalation and theophylline sustained-release