中西医结合治疗早期帕金森病患者运动症状随访研究.docVIP

中西医结合治疗早期帕金森病患者运动症状的随访研究 　　【摘要】 目的 探讨中西医结合治疗早期帕金森病患者运动症状的有效性。方法 38例早期帕金森病患者随机分为治疗组和对照组。治疗组19例患者常规给予金刚烷胺片治疗的基础上， 内服平肝止颤汤治疗4周， 对照组19例患者单纯给予金刚烷胺片治疗。观察两组治疗疗效。结果 治疗组治疗后4周运动症状的改善与对照组比较差异有统计学意义（P0.05）， 4周后停服中药， 随访至12周治疗组运动症状评分优于对照组（P0.05）。结论 中西医结合治疗早期帕金森病可更好地改善患者运动症状， 提高疗效。 　　【关键词】 中西医结合；帕金森病；运动症状 　　【Abstract】 Objective To investigate the effectiveness of integrated Chinese and Western medicines in the treatment of motor symptoms in patients with early Parkinsons disease. Methods A total of 38 patients with early Parkinsons disease were randomly divided into treatment group and control group. The treatment group with 19 cases received oral Pinggan Zhichan decoction for 4 weeks， in addition to conventional amantadine tablets treatment. The control group was treated by single therapy of amantadine tablets. The curative effects of the two groups were observed. Results After 4-week treatment， there was statistically significant difference of improved motor symptoms between the treatment group and control group （P0.05）. The traditional Chinese medicine was withdrawn after 4 weeks， and the treatment group had higher scores of motor symptoms in 12 weeks of follow-up than the control group （P0.05）. Conclusion The application of integrated Chinese and Western medicines can remarkably improve patients’ motor symptoms， and enhance curative effect. 　　【Key words】 Integrated Chinese and Western medicines； Parkinsons disease； Motor symptoms 　　中西医结合治疗早期帕金森病患者运动症状的随访研究 　　王明红 吴玉涛 张亚蓬 　　【摘要】 目的 探讨中西医结合治疗早期帕金森病患者运动症状的有效性。方法 38例早期帕金森病患者随机分为治疗组和对照组。治疗组19例患者常规给予金刚烷胺片治疗的基础上， 内服平肝止颤汤治疗4周， 对照组19例患者单纯给予金刚烷胺片治疗。观察两组治疗疗效。结果 治疗组治疗后4周运动症状的改善与对照组比较差异有统计学意义（P0.05）， 4周后停服中药， 随访至12周治疗组运动症状评分优于对照组（P0.05）。结论 中西医结合治疗早期帕金森病可更好地改善患者运动症状， 提高疗效。 　　【关键词】 中西医结合；帕金森病；运动症状 　　DOI：10.14163/j.cnki.11-5547/r.2015.02.014 　　Follow-up research of integrated Chinese and Western medicines in the treatment of motor symptoms in patients with early Parkinsons disease WANG Ming-hong， WU Yu-tao， ZHANG Ya-peng. Department