中西医结合治疗甲状腺功能亢进症及对患者骨代谢指标和骨密度影响.docVIP

中西医结合治疗甲状腺功能亢进症及对患者骨代谢指标和骨密度的影响 　　[摘要]目的 ?^察中西医结合治疗甲状腺功能亢进症的临床效果及对患者骨代谢指标和骨密度的影响。方法 回顾性分析2015年3月～2016年3月期间我院收治的甲状腺功能亢进症患者67例，根据治疗方法分为两组，对照组31例给予西医常规治疗；治疗组36例在对照组基础上给予中药口服治疗，并比较治疗前后两组患者临床疗效及患者骨代谢指标和骨密度差异。结果 治疗组总有效率为88.9%，高于对照组74.2%（P0.05）；两组患者治疗后FT3、FT4水平均较治疗前明显降低，TSH明显升高 （P0.05），治疗组治疗后FT3、FT4水平均优于对照组（P0.05）；两组治疗后CT、BGP、ALP、PINP水平均明显改善，治疗后骨密度较治疗前均明显改善，且治疗组均优于对照组。结论 中西医结合治疗甲状腺功能亢进症，能够显著改善患者甲状腺功能，纠正骨代谢异常和增加骨密度。 　　[关键词] 甲状腺功能亢进症；中西医结合；甲状腺功能；骨代谢指标；骨密度 　　[中图分类号] R581.1 [文献标识码] A [文章编号] 2095-0616（2017）07-27-04 　　Influence of combine traditional Chinese and western medicine in the treatment of hyperthyroidism and its effects on bone turnover markers and bone mineral density 　　ZHENG Xiaodong 　　Department of Endocrinology， the TCM Hospital of Liaocheng City， Liaocheng 252000， China 　　[Abstract] Objective To observe the clinical effects of combine traditional Chinese and western medicine in the treatment of hyperthyroidism and its effect onbone turnover markers and hone mineral density. Methods 67 cases of hyperthyroidism patients in March 2015 to March 2016 were retrospectively analyzed in our hospital， according to the treatment were divided into two groups， 31 cases were given western medicine routine treatment in the control group， treatment group （36 cases） on the basis of giving oral medicine treatment， and the clinical efficacy before and after the treatment， bone metabolic index and bone mineral density of two groups of patients were compared. Results The total effective rate was 88.9% in the treatment group was higher than 74.2% in the oontrol group（P0.05）. The levels of FT3， FT4 and TSH in the two groups were better than those in the control group（P0.05）. The levels of FT3 and FT4 in two groups of patients after treatment were significantly lower than before treatment， and TSH significantly increased（P0.05）. The levels of FT3， FT4 in the treatment group were better than those in the control group（P0.05） .After treatment， both the CT， BGP， ALP and PINP were si