中西药结合治疗肥厚型心肌病临床和预后分析.docVIP

中西药结合治疗肥厚型心肌病的临床和预后分析 　　[摘要] 目的 探讨中西药结合治疗肥厚型心肌病的临床和预后。 方法 肥厚型心肌病患者80例根据挂号单双号分为治疗组与对照组各40例，对照组给予倍他乐克治疗，治疗组在此基础上给予自拟中药汤治疗。 结果 治疗后治疗组的LVPWT和IVST值明显低于对照组，而LVDd值明显高于对照组，对比差异有统计学意义（P0.05）。治疗组与对照组的总有效率分别为82.5%和70.0%，组间对比差异有统计学意义（P0.05）。 结论 中西药结合治疗肥厚型心肌病能有效改善心肌指标，提高治疗疗效，值得临床推广应用。 　　[关键词] 中西药结合治疗；肥厚型心肌病；超声心动图 　　[中图分类号] R542.2 [文献标识码] B [文章编号] 2095-0616（2013）24-96-02 　　Analysis on the clinical features and prognosis of hypertrophic cardiomyopathy treated by integrative medicine 　　HUANG Qian 　　Department of Internal Medicine，Yongcheng City Peoples Hospital in Henan Province，Yongcheng 476600，China 　　[Abstract] Objective To explore the clinical features and prognosis of hypertrophic cardiomyopathy treated by integrative medicine. Methods 80 patients with hypertrophic cardiomyopathy were randomly assigned to the treatment group and the control group according to the registration number （odd or even）.Each group contained 40 cases.The control group was treated with metoprolol， and the treatment group was treated with traditional Chinese medicine decoction in addition to metoprolol. Results The treatment group had lower LVPWT and IVST，and higher LVDd than the control group after treatment，with statistical significance （P0.05）.The total effective rate of the treatment group and the control group was 82.5% and 70.0% respectively， with statistical significance（P0.05）. Conclusion Application of integrative medicine for treatment of hypertrophic cardiomyopathy can significantly improve cardiac index and therapeutic efficacy，which is worthy of clinical application. 　　[Key words] Integrative medicine；Hypertrophic cardiomyopathy；Echocardiography 　　当前在我国由于社会竞争的日趋激烈以及不良生活行为习惯的影响，肥厚型心肌病的发病率有逐年增高趋势[1]。其临床病理主要表现心肌肥厚、心肌纤维化、心肌细胞排列紊乱，预后比较差，可造成心脏性猝死[2]。临床主要表现为心室充盈增加、心肌舒张功能减弱、劳力性呼吸困难心绞痛，直至表现为晕厥、恶性室性心律失常、心功能减退或衰竭[3]。研究发现现代西药有其严重的致心律失常作用和增加死亡率的危险[4]。本研究从中医学理论入手，旨在探讨中西药结合治疗肥厚型梗阻型心肌病的临床和预后效果，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取我院于2010年1月～2013年2月收治的肥厚型梗阻型心肌病患者80例，入选标准：符合肥厚型心肌病的诊断标准；已服用其他药物治疗需停药2周