介入有氧运动及肺康复训练联合吸入舒利迭与噻托溴铵对中重度COPD患者肺功能运动耐力及生活质量影响.docVIP

介入有氧运动及肺康复训练联合吸入舒利迭与噻托溴铵对中重度COPD患者肺功能、运动耐力及生活质量的影响 　　[摘要] 目的 探?介入有氧运动及肺康复训练联合吸入舒利迭与噻托溴铵对中重度慢性阻塞性肺疾病（COPD）患者肺功能、运动耐力及生活质量的影响。 方法 选取西安医学院附属医院2013年7月～2015年7月收治的147例中重度COPD患者，将其随机分为试验组1、试验组2和对照组，各49例。对照组采用药物治疗，试验组1采用有氧运动进行干预，试验组2采用有氧运动联合肺康复训练及药物干预。干预8周后，观察三组患者的肺功能、运动耐力及生活质量的变化。 结果 试验组2的肺活量、用力肺活量、最大通气量均明显优于对照组和试验组1，差异有统计学意义（P 0.05）；试验组2的分泌型免疫球蛋白A、去甲肾上腺素含量均显著低于对照组和试验组1，差异均有统计学意义（P 0.05）。试验组2的6 min步行试验明显高于对照组和试验组1，生活质量评分明显低于对照组和试验组1，差异均有统计学意义（P 0.05）。 结论 对中重度COPD患者进行综合有氧运动及肺康复训练联合吸入舒利迭与噻托溴铵干预可以提高患者的肺功能、运动耐力和生活质量，值得推广应用。 　　[关键词] 中重度慢性阻塞性肺疾病；综合有氧运动；肺康复训练；舒利迭；噻托溴铵；肺功能；运动耐力；生活质量 　　[中图分类号] R563.1 [文献标识码] A [文章编号] 1673-7210（2017）06（b）-0104-04 　　Effect of the intervention of aerobic exercise and pulmonary rehabilitation training combined with inhalation of Seretide and Tiotropium Bromide for the pulmonary function， exercise tolerance and quality of life in patients with moderate-severe COPD 　　HU Liangbin1 YANG Jianquan2 　　1.Department of Sports， Shangluo Vocational and Technical College， Shaanxi Province， Shangluo 726000， China； 2.Department of Sports， Xian Medical University， Shaanxi Province， Xian 710021， China 　　[Abstract] Objective To explore the effects of the intervention of aerobic exercise and pulmonary rehabilitation training combined with inhalation of Seretide and Tiotropium Bromide for the pulmonary function， exercise tolerance and quality of life in patients with moderate-severe chronic obstructive pulmonary disease （COPD）. Methods One hundred and forty-seven patients with moderate-severe COPD admitted to the Affiliated Hospital of Xian Medical University from July 2013 to July 2015 were selected and randomly divided into experimental group 1， experimental group 2 and control group， with 49 cases in each group. The control group was given drug therapy， the experimental group 1 was given aerobic exercise intervention， the experimental group 2 was given the aerobic exercise combined with pulmonary rehabilitation training and drug intervention. After interven