介入化疗栓塞联合腹部热疗治疗晚期胃癌近远期疗效探讨.docVIP

介入化疗栓塞联合腹部热疗治疗晚期胃癌的近远期疗效探讨 　　[摘要]目的 探讨介入化疗栓塞联合腹部热疗治疗晚期胃癌的近远期疗效。方法 选取该院收治的129例晚期胃癌患者为研究对象，根据其意愿分成A、B、C3组，A、B组均予以介入化疗栓塞方案，其中A组同时联合腹部热疗；C组则采用紫杉醇+顺铂化疗方案。行为期3年随访，比对3组患者近、远期疗效及生存率，分析其不良反应发生情况，记录其生活质量评估差异。结果 A组近远期疗效及生活质量评估结果为3组最佳，其次为B组，C组最差（P0.05），但均优于C组（P0.05）。结论 对晚期胃癌患者予以介入化疗栓塞联合腹部热疗方案，近远期治疗效果均较为理想，不良反应较低，利于提高患者生存率及生存质量，值得临床推广。 　　[关键词]介入化疗栓塞；腹部热疗；晚期；胃癌 　　[中图分类号]R59 [文献标识码]A [文章编号]1674-0742（2015）04（b）-0044-02 　　Observation on Short-term and Long-term Therapeutic Effects of Interventional Chemotherapy and Embolization Combined with Abdominal Thermotherapy in the Treatment of Advanced Gastric Cancer 　　JIANG Ming GAO Xiaopan LU Xiao LAI Fengyong 　　Interventional Department， Henan Province Anyang tumor hospital， Anyang， Henan Province， 455000 China 　　[Abstract] Objective To investigate the recent and long-term efficacy of interventional chemotherapy and embolization combined with abdominal thermotherapy in treatment of advanced gastric cancer. Methods 129 cases of advanced gastric cancer patients were selected as the subjects， according to its intention were divided into group A， group B， group C three groups， group A， group B were treated with interventional chemotherapy and embolization scheme， in which group A at the same time combined with abdominal thermotherapy； group C were treated with paclitaxel + cisplatin chemotherapy. Followed-up 3 year， compared behavior， near， long-term effect and survival rate in the three groups， analysis of toxic side reaction patients， recorded differences of evaluation of life quality. Results The short and long-term curative effect and quality of life assessment results in group A was the best of three groups， followed by group B， group C was the worst （P0.05）， and were better than group C（P0.05）. Conclusion Interventional chemoembolization combined with abdominal thermotherapy scheme on patients with advanced gastric cancer， the therapeutic effects is more ideal， toxicity is lower， can improve the survival rate and survival qualit