保乳手术治疗早期乳腺癌疗效及安全性探究.docVIP

保乳手术治疗早期乳腺癌的疗效及安全性探究 　　[摘要] 目的 探讨比较保乳手术与改良根治术治疗早期乳腺癌的疗效及安全性。方法 将2008年3月―2011年1月在该院行手术治疗的101例早期乳腺癌患者按所行术式不同随机分为观察组（53例，施行保乳手术治疗）和对照组（48例，行改良根治术治疗），对两种术式的手术情况及术后随访情况进行综合比较。 结果 观察组患者手术耗时（117.0±25.7）min、术中出血量（142.4±35.0）mL、术后引流时间（8.2±4.6）d均明显少于对照组[（169.5±24.3）min、（217.5±43.1）mL、（13.1±5.3）d]（P0.05）；观察组术后乳房美观效果显著优于对照组（P0.01）。 结论 保乳手术治疗早期乳腺癌在远期疗效方面与改良根治术相当，但保乳手术在保持乳房美观效果方面更优。 　　[关键词] 保乳手术；改良根治术；早期乳腺癌 　　[中图分类号] R737.9 [文献标识码] A [文章编号] 1674-0742（2014）08（b）-0023-02 　　[Abstract] Objective To observe and compare the efficacy and safety between breast conserving operation and modified radical mastectomy in treating early breast cancer. Methods 101 patients with early breast cancer underwent surgical treatment in our hospital from March 2008 to January 2011 were randomly divided into the observation group （53 cases， were given breast conserving operation）， control group （48 cases， were given modified radical mastectomy） according to different operation given to the patients. And the operative status and postoperative follow-up conditions of the two groups were comprehensively compared. Results The operative time， intraoperative blood loss， postoperative drainage time of the observation group was（117.0±25.7）min，（142.4±35.0）mL， （8.2±4.6）d， respectively， less than （169.5±24.3）min，（217.5±43.1）mL， and （13.1±5.3）d of the control group， respectively （P0.05）； The postoperatively aesthetic effect of breast in the observation group was much better than that in the control group（P0.01）. Conclusion Both breast conserving operation and modified radical mastectomy have good long-term effect on treating early breast cancer， but the breast conserving operation can keep better aesthetic effect of breast. 　　[Key words] Breast conserving operation； Modified radical mastectomy； Early breast cancer 　　随着现代医疗技术水平的不断提高，新型的保乳手术受到越来越多早期乳腺癌患者青睐，保乳手术虽然能够为早期乳腺癌保留乳房，但其在远期疗效方面是否能够与改良根治术相当仍有较大争议[1-2]。为此，该研究通过将2008年3月―2011年1月该院采用保乳手术与改良根治术治疗的共计101例患者的远期疗效及术后美观效果进行观察比较，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取在该