生长激素药品说明书法律地位和价值.pptVIP

GH抗体无临床意义，已形成共识30余年 1987—1999 1. R. Gunnarsson,?P. Wilton.Clinical Experience with Genotropin Worldwide: An Update March 1987. Acta Paediatr Scand [Suppl] 337-147, 1987. 2. F. Buzi, C. R. Buchanan, D. J. Morrell,etc..Antigenicity and efficacy of authentic sequence recombinant human growth hormon（somatropin）：First-year experime-nce in the United Kingdom. Clinical Endocrinology 30, 531-538,1989. 3. Rougeot?C.?,?Marchand?P.M.,·?Dray?F..etc. Comparative Study of Biosynthetic Human Growth Hormone Immunogenicity in Growth Hormone Deficient Children. Horm Res 15:76–81,1991. 4. K. Lundin,?L. Be