儿童肺炎支原体肺炎合并胸腔积液临床特征及实验室检查结果分析.docVIP

儿童肺炎支原体肺炎合并胸腔积液临床特征及实验室检查结果分析 　　【摘要】目的探?并比较儿童肺炎支原体肺炎（MPP）及MPP合并胸腔积液（PE）的临床及实验室检查特征，为临床诊治提供依据。 　　方法回顾性分析2015年1月至2016年12月住院的MPP患儿共774 例，分为单纯MPP组716 例及MPP合并PE组58 例，收集临床及实验室检查资料并分析。 　　结果单纯MPP组平均年龄为（3.17±2.66）岁，MPP合并PE组平均年龄为（5.10±2.55）岁，差异有统计学意义（P0.05），后者学龄期儿童比例占41.4%，差异有统计学意义（P0.05）。MPP合并PE组的热程及住院时间均长于单纯MPP组，差异有统计学意义（P0.01）。MPP合并PE组多为以肺实变为主的大叶性肺炎（82.8%），高于单纯MPP组（22.5%），差异有统计学意义（P0.01）。MPP合并PE组的CRP及LDH值均高于单纯MPP组，差异有统计学意义（P0.05）。MPP合并PE组的CD3+、CD3+CD4+T淋巴细胞比例和CD4+/CD8+比值均低于单纯MPP组（ P0.01），而CD3+CD8+T淋巴细胞比例则高于后者（P0.01） 。MPP合并PE组的IgA值高于单纯MPP组（P0.05），而IgM、IgG值两组间差异无统计学意义。 　　结论MPP合并胸腔积液时患儿的临床特征及实验室检查结果与单纯MPP患儿存在明显差异，证实MPP并发胸腔积液时存在更为严重的免疫损伤。 　　【关键词】肺炎支原体；肺炎；胸腔积液；儿童 　　中图分类号：R725 文献标识码：ADOI：10.3969/j.issn2017.05.005 　　Analysis of clinical characteristics and laboratory examination results of children with MPP complicated with PE 　　[HJ2][HJ] 　　WANG Zhe，LI Yuqin，LUO Yali，DING Ying，CHU Chu，ZHOU Weifang▲ 　　（Department of Infectious Disease，Children’s Hospital Affiliated to Suzhou University，Suzhou 215003，China） 　　[HJ2][HJ] 　　【Abstract】ObjectiveTo explore and compare the clinical characteristics and laboratory examination results of children with MPP（mycoplasma pneumoniae pneumonia）complicated with PE（pleural effusion），so as to provide basis for clinical diagnosis and treatment. 　　Methods774 children hospitalized in hospital during January，2015 to December，2016 were analyzed retrospectively.All patients were divided into MPP group（n=716） and MPP+PE group（n=58）.Clinical data and laboratory results were collected and analyzed. 　　ResultsThe average age of the MPP group was（3.17±2.66）year，and that of the MPP + PE group was（5.10±2.55）year，difference was statistically significant（P 　　ConclusionThere is significantly statistical difference in clinical characteristics and laboratory examination results between the two groups，which confirms that MPP combined with PE has more severe immune damage. 　　【Key words】mycoplasma pneumoniae；pneumonia；PE；children 　　肺炎支原体肺炎（Mycop