化瘀接骨散对上肢闭合性骨折愈合情况影响及不良反应分析.docVIP

化瘀接骨散对上肢闭合性骨折愈合情况影响及不良反应分析 　　[摘要]目的 探?化瘀接骨散对上肢闭合性骨折愈合情况的影响及不良反应。方法 收集2016年1月～2017年6月我院中医骨伤科收治的上肢闭合性骨折患者120例，采用随机数字表法将患者分为对照组（n=60）和观察组（n=60），对照组采用常规手法复位夹板，观察组在对照组治疗基础上加用化瘀接骨散外敷，治疗周期均为45 d。观察两组患者的临床疗效，骨折愈合时间，术后第1、3、5、7、9周的X线片检查结果及不良反应发生情况。结果 经过45 d的治疗，观察组患者的总有效率（95.0%）显著高于对照组（85.0%），差异有统计学意义（P0.05）；观察组患者术后第5、7、9周的X线片评分均显著高于对照组，差异有统计学意义（P0.05）。观察组患者的骨折愈合时间较对照组显著缩短（P0.05）；此外，治疗过程中，观察组共发生9例不良反应，主要表现为皮肤瘙痒，经治疗后症状消失，未对结果产生不良影响。结论 化瘀接骨散外敷辅助治疗能显著提高常规手法复位夹板固定治疗上肢闭合性骨折的临床效果，缩短骨折愈合时间，提高X线片评分，减少不良反应，值得临床推广应用。 　　[关键词]化瘀接骨散；上肢闭合性骨折；骨折愈合情况；不良反应 　　[中图分类号] R944.2+4 [文献标识码] A [文章编号] 1674-4721（2017）08（c）-0095-03 　　[Abstract]Objective To investigate the influence of Huayu Tonggu Powder on the healing of upper limb closed fracture and the adverse reaction.Methods A total of 120 patients with upper limb closed fracture treated in department of Orthopedics and Traumatology from January 2016 to June 2017 were collected.The patients were divided into control group （n=60） and observation group （n=60） using the random number table method.The patients in control group were treated by conventional manual reduction splint while the patients in observation group treated by Huayu Jiegu Powder for external application based on the treatment of the control group.Treatment cycles were 45 days.Clinical curative effect in the two groups were observed，and fracture healing time，limb pain，swelling degree score，X-ray examination results after the 1st，3rd，5th，7th，9th week operation and adverse reactions of patients in the two groups were observed.Results After 45 days of treatment，the total effective rate was 95.0% in the observation group，which was significantly higher than that in the control group （85.0%） （P0.05）.The X-ray score of patients in observation group were obviously higher than those of control group after the 5th，7th，9th week operation （P0.05）.The healing time of fracture in observation group was significantly shorter than that of control group （P0.05）.During the course of treatment，9 case