双水平无创正压通气应用于慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者临床效果观察.docVIP

双水平无创正压通气应用于慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者临床效果观察 　　[摘要] 目的 探讨双水平无创正压通气（BiPAP）对慢性阻塞性肺疾病（COPD）合并Ⅱ型呼吸衰竭的临床疗效。 方法 根据是否在常规治疗的基础上结合双水平无创 BiPAP 呼吸机治疗，将54例COPD 合并Ⅱ型呼吸衰竭患者分为观察组（27例）和对照组（27例）。比较两组患者的治疗效果、血气分析结果及生命体征的变化等指标。 结果 经治疗，观察组血气指标、心率、呼吸频率的改善水平，显著优于对照组（P0.05）。 结论 双水平无创呼吸机对于慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭在临床操作中表现出良好的有效性和安全性，值得临床使用。 　　[关键词] 双水平无创正压通气；慢性阻塞性肺疾病；Ⅱ型呼吸衰竭；临床效果 　　[中图分类号] R563.9 [文献标识码] B [文章编号] 2095-0616（2015）14-183-03 　　Effect of bilevel positive airway pressure ventilation on chronic obstruction pulmonary disease complicated with type Ⅱ respiratory failure 　　LAO Jinbo LIU Hui ZENG Yunping 　　Department of Respiratory Medicine， Zhanjiang City Second Hospital， Zhanjiang 524013， China 　　[Abstract] Objective To explore the effect of bilevel positive airway pressure ventilation （BiPAP） on chronic obstructive pulmonary disease （COPD） complicated with typeⅡrespiratory failure. Methods A total of 54 patients with COPD complicated with type Ⅱ respiratory failure were selected， and divided into treatment group（27 patients） and control group（27 patients） according to whether or not used noninvasive BiPAP ventilation therapy on the basis of conventional treatment. Therapeutic effect， the result of blood gas analysis and vital signs were compared between two groups after treatment. Results After treatment， the improvement of blood gas index， heart rate and respiratory frequency in treatment group were better than control group； the average hospitalization time in treatment group was shorter than control group， there was a significant difference between two groups （P0.05）. Conclusion BiPAP is safe and effective on treating patients with COPD complicated with type Ⅱ respiratory failure， which is worthy of clinical use. 　　[Key words] Bilevel positive airway pressure ventilation； Chronic obstructive pulmonary disease； TypeⅡ respiratory failure； Clinical effect 　　Ⅱ型呼吸衰竭，是慢性阻塞性肺疾病（COPD）的常见并发症，是COPD发展到严重阶段的表现，临床发病率高，病情复杂，会引起多器官损伤，病死率高。由于病情轻重、缓急不同，且受机体代偿情况及治疗措施等影响，可出现多种类型酸碱失调及生命体征的变化[1]。近年来，双水平无创正压