地佐辛不同给药方式用于瑞芬太尼复合麻醉术后苏醒期拔管及镇痛镇静效果影响分析.docVIP

地佐辛不同给药方式用于瑞芬太尼复合麻醉术后苏醒期拔管及镇痛镇静效果影响分析 　　[摘要] 目的 探讨地佐辛不同给药方式用于瑞芬太尼复合麻醉术后苏醒期拔管及镇痛镇静效果的影响。方法 方便选取该院麻醉术后苏醒期患者120例，选取时间为2015年1―10月，选择随机的方式对该院所有观察对象进行分组（均采用瑞芬太尼复合麻醉），分为对照组-静脉注射地佐辛，观察组-肌肉注射地佐辛，每组患者60例，比较2组临床指标、不良反应发生情况。结果 观察组麻醉术后苏醒期患者苏醒时间（4.45±0.35）min、气管拔管时间（8.22±1.35）min、镇静评分（3.34±1.86）分、镇痛评分（2.21±0.25）分，显著优于对照组各项指标（P0.05）。观察组麻醉术后苏醒期患者不良反应发生率1.67%，显著低于对照组20.00%，2组间相比较差异有统计学意义（P0.05）。结论 对麻醉术后苏醒期患者采用肌肉注射地佐辛，能够达到显著的镇痛镇静效果，同时还能有效降低其不良反应发生率，值得研究。 　　[关键词] 地佐辛；不同给药方式；瑞芬太尼；苏醒期拔管；镇痛镇静 　　[中图分类号] R614 [文献标识码] A [文章编号] 1674-0742（2018）01（c）-0115-04 　　[Abstract] Objective This paper tries to observe the effect of different administrations of dezocine on tracheal extubation and analgesic sedation after remifentanil combined anesthesia. Methods A total of 120 patients were recruited during the recovery period of anesthesia in this hospital （from January to October 2015）， all subjects were randomly divided into groups （remifentanil anesthesia was used）， divided into control group - intravenous dezocine， observation group - intramuscular injection of dezocine， with 60 patients in each group， compared two groups of clinical indicators， the incidence of adverse reactions. Results The awakening time （4.45±0.35）min， tracheal extubation time（8.22±1.35）min， sedation score （3.34±1.86）points and analgesic score （2.21±0.25）points in the observation group， better than the control group（P0.05）. In the observation group， the incidence of adverse reactions was 1.67% in the awakening patients， which was significantly lower than that in the control group of 20.00%，the difference was stntistically significant（P0.05）. Conclusion Intravenous injection of dezocine in patients with recuperation after anesthesia can achieve significant analgesic and sedative effects， and can effectively reduce the incidence of adverse reactions， it is worth studying. 　　[Key words] Dezocine； Different modes of administration； Remifentanil； Recovery extubation； Analgesic sedation 　　瑞芬太尼在?R床上十分常见，常应用于麻醉诱导中，具有较好的麻醉效果，但由于其麻